DOI . ORG {
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Title[redir]:
Effects of Iron Ions and Iron Chelation on the Efficiency of Experimental Radiotherapy of Animals with Gliomas | Bulletin of Experimental Biology and Medicine
Description:
We evaluated the effect of iron ion chelation on the growth of gliomas and radiotherapy efficiency in tumor-bearing animals. The rats with transplanted glioma-35 received iron-containing water; desferroxamine was injected for metal chelation. Long-term treatment with iron-containing water promoted glioma growth in rats and improved the efficiency of radiotherapy due to combination of apoptosis and ferroptosis. Desferroxamine reduced the efficiency of this treatment and was inessential for the efficiency of radiotherapy alone.
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article, google, scholar, cas, pubmed, iron, ivanov, efficiency, radiotherapy, kovanko, privacy, cookies, content, semenov, access, cancer, information, publish, research, search, experimental, chelation, gliomas, biol, data, log, journal, ions, animals, april, rats, glioma, desferroxamine, discover, med, download, author, springer, optional, personal, parties, policy, find, track, bulletin, biology, medicine, effects, published, cite,
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month download article/chapter byulleten’ eksperimental’noi biologii cas google scholar article google scholar privacy choices/manage cookies full article pdf iron chelator deferasirox iron ion chelation google scholar european economic area related subjects iron ions conditions privacy policy accepting optional cookies article bulletin long-term treatment check access instant access tumor-bearing animals main content log journal finder publish author correspondence article log iron chelation cancer sci cancer prev cancer inst desferroxamine reduced article cite privacy policy personal data article ivanov gliomas published december books a experimental radiotherapy radiotherapy due optional cookies manage preferences russian federation data protection essential cookies cookies skip subscription content similar content medicine aims institution subscribe journal publish radiotherapy efficiency desferroxamine
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headline:Effects of Iron Ions and Iron Chelation on the Efficiency of Experimental Radiotherapy of Animals with Gliomas
description:We evaluated the effect of iron ion chelation on the growth of gliomas and radiotherapy efficiency in tumor-bearing animals. The rats with transplanted glioma-35 received iron-containing water; desferroxamine was injected for metal chelation. Long-term treatment with iron-containing water promoted glioma growth in rats and improved the efficiency of radiotherapy due to combination of apoptosis and ferroptosis. Desferroxamine reduced the efficiency of this treatment and was inessential for the efficiency of radiotherapy alone.
datePublished:2015-04-22T00:00:00Z
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headline:Effects of Iron Ions and Iron Chelation on the Efficiency of Experimental Radiotherapy of Animals with Gliomas
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