DOI . ORG {
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Title[redir]:
Wilson’s disease—cause of mortality in 164 patients during 1992–2003 observation period | Journal of Neurology
Description:
We studied the cause of death in a consecutive series of 164 patients with Wilson’s disease (WD) diagnosed over an 11 year period. A total of 20 [12% (95% CI 10.3–16.0)] died during the observation period. The relative survival rate of all patients in our group was statistically smaller than in Polish population. The main cause of death was the diagnosis in advanced stage of disease, but in six patients presenting with mild signs, we observed the progression of the disease despite treatment. There was no difference in mortality rate in patients treated with dpenicillamine or zinc sulphate as initial therapy. The prognosis for survival in the majority of WD patients is favourable, provided that therapy is introduced early.
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disease, google, scholar, wilsons, article, pubmed, cas, patients, członkowska, treatment, therapy, neurol, privacy, cookies, content, journal, mortality, survival, access, walshe, data, publish, search, observation, period, rodo, wilson, liver, hepatocellular, carcinoma, med, information, log, research, tarnacka, litwin, gajda, dpenicillamine, zinc, initial, prognosis, discover, penicillamine, arch, ofwilsons, copper, clin, download, author, springer,
Topics {✒️}
month download article/chapter liver copper concentration privacy choices/manage cookies full article pdf related subjects walshe jm relative survival rate relative survival analysis european economic area scope submit manuscript long-term follow intestinal metallothionein induction conditions privacy policy computer program package anti-copper agents long-term treatment accepting optional cookies yusbasiyan-gurkan journal finder publish article journal interrupting penicillamine therapy article członkowska wilson disease gene personal data liver 12 article log initial penicillamine therapy author correspondence check access instant access mortality rate article cite data protection privacy policy books a observation period 1992–2003 observation period optional cookies manage preferences journal publish subscription content similar content 11 year period essential cookies cookies skip usage analysis neurology aims initial therapy computer programs institution subscribe
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headline:Wilson’s disease—cause of mortality in 164 patients during 1992–2003 observation period
description:We studied the cause
of death in a consecutive series of
164 patients with Wilson’s disease
(WD) diagnosed over an 11 year
period. A total of 20 [12% (95% CI
10.3–16.0)] died during the observation
period. The relative survival
rate of all patients in our group was
statistically smaller than in Polish
population. The main cause of
death was the diagnosis in advanced
stage of disease, but in six
patients presenting with mild
signs, we observed the progression
of the disease despite treatment.
There was no difference in mortality
rate in patients treated with dpenicillamine
or zinc sulphate as
initial therapy. The prognosis for survival in
the majority of WD patients is
favourable, provided that therapy is
introduced early.
datePublished:2005-03-02T00:00:00Z
dateModified:2005-03-02T00:00:00Z
pageStart:698
pageEnd:703
sameAs:https://doi.org/10.1007/s00415-005-0720-4
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Wilson’s disease
mortality
treatment
Neurology
Neurosciences
Neuroradiology
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headline:Wilson’s disease—cause of mortality in 164 patients during 1992–2003 observation period
description:We studied the cause
of death in a consecutive series of
164 patients with Wilson’s disease
(WD) diagnosed over an 11 year
period. A total of 20 [12% (95% CI
10.3–16.0)] died during the observation
period. The relative survival
rate of all patients in our group was
statistically smaller than in Polish
population. The main cause of
death was the diagnosis in advanced
stage of disease, but in six
patients presenting with mild
signs, we observed the progression
of the disease despite treatment.
There was no difference in mortality
rate in patients treated with dpenicillamine
or zinc sulphate as
initial therapy. The prognosis for survival in
the majority of WD patients is
favourable, provided that therapy is
introduced early.
datePublished:2005-03-02T00:00:00Z
dateModified:2005-03-02T00:00:00Z
pageStart:698
pageEnd:703
sameAs:https://doi.org/10.1007/s00415-005-0720-4
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Wilson’s disease
mortality
treatment
Neurology
Neurosciences
Neuroradiology
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