
DOI . ORG {
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Title[redir]:
Meeting report from the 2nd International Symposium on New Frontiers in Cardiovascular Research. Protecting the cardiovascular system from ischemia: between bench and bedside | Basic Research in Cardiology
Description:
Recent advances in basic cardiovascular research as well as their translation into the clinical situation were the focus at the last âNew Frontiers in Cardiovascular Research meetingâ. Major topics included the characterization of new targets and procedures in cardioprotection, deciphering new players and inflammatory mechanisms in ischemic heart disease as well as uncovering microRNAs and other biomarkers as versatile and possibly causal factors in cardiovascular pathogenesis. Although a number of pathological situations such as ischemiaâreperfusion injury or atherosclerosis can be simulated and manipulated in diverse animal models, also to challenge new drugs for intervention, patient studies are the ultimate litmus test to obtain unequivocal information about the validity of biomedical concepts and their application in the clinics. Thus, the open and bidirectional exchange between bench and bedside is crucial to advance the field of ischemic heart disease with a particular emphasis of understanding long-lasting approaches in cardioprotection.
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Keywords {đ}
pubmed, article, google, scholar, cas, heart, myocardial, cardiovascular, research, cardiac, patients, cardioprotection, clinical, ischemic, cell, injury, acute, res, central, hausenloy, mitochondrial, infarction, cardioprotective, role, remote, cardiol, iri, cabrerafuentes, heusch, university, mayr, disease, therapeutic, institute, basic, coronary, endothelial, ischemiareperfusion, conditioning, yellon, proteins, vascular, platelet, reperfusion, data, liehn, targets, inflammatory, atherosclerosis, preconditioning,
Topics {âïž}
int/mediacentre/factsheets/fs317/en/ willeit mouse macrophage-colony-stimulating factor high-density lipoprotein s2010/bmd-2542 acronimo âconsepoc-cmâ mouse bone marrow-derived-macrophages hypoxia-inducible factors hif-1α high-density lipoproteins s-nitrosylated mif-mediated cardioprotection ischemia-provoked hif-2α activation ÎČ-n-acetyl-glucosamine monocyte/macrophage polarisation article download pdf hypoxia-inducible factor-2alpha cardiac myosin-binding protein centro de biotecnologĂa-femsa improves long-term outcome glycogen synthase kinase-3beta ve-cadherin adhesion plaques sang-bing ong & derek natural anti-atherogenic drug macrophage polarization actin/myosin-mediated contractility cxcr2/4-mediated leukocyte recruitment ve-cadherin/catenin complex transient arm ischemia/reperfusion myocardial ischemia/reperfusion injury glycogen synthase kinase-3ÎČ cardiac ischemia-reperfusion injury article cabrera-fuentes acute ischemia/reperfusion injury adriana sumoza-toledo tumour necrosis factor-alpha temporary pro-inflammatory factor regulating endothelial permeability cardiac ischaemia/reperfusion injury tnf-α converting enzyme numerous inflammation-related genes hatter cardiovascular institute anti-inflammatory therapeutic strategy tumor-necrosis-factor α hatter workshop recommendations lysosomal ca2+-release channel understanding long-lasting approaches porcine ischemia-reperfusion model targeting endothelial permeability coronary artery disease efficient post-ischemic reduction cutting-edge postgenomics technologies sang-bing ong translocated gsk-3ÎČ interacted
Questions {â}
- Giannitsis E, Katus HA (2015) A long way to translation: will cMyC survive?
- Heusch G (2015) CIRCUS: a kiss of death for cardioprotection?
- Heusch G, Gersh BJ (2015) ERICCA and RIPHeart: two nails in the coffin for cardioprotection by remote ischemic conditioning?
- Is ischemia the only factor predicting cardiovascular outcomes in all diabetes mellitus patients?
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headline:Meeting report from the 2nd International Symposium on New Frontiers in Cardiovascular Research. Protecting the cardiovascular system from ischemia: between bench and bedside
description:Recent advances in basic cardiovascular research as well as their translation into the clinical situation were the focus at the last âNew Frontiers in Cardiovascular Research meetingâ. Major topics included the characterization of new targets and procedures in cardioprotection, deciphering new players and inflammatory mechanisms in ischemic heart disease as well as uncovering microRNAs and other biomarkers as versatile and possibly causal factors in cardiovascular pathogenesis. Although a number of pathological situations such as ischemiaâreperfusion injury or atherosclerosis can be simulated and manipulated in diverse animal models, also to challenge new drugs for intervention, patient studies are the ultimate litmus test to obtain unequivocal information about the validity of biomedical concepts and their application in the clinics. Thus, the open and bidirectional exchange between bench and bedside is crucial to advance the field of ischemic heart disease with a particular emphasis of understanding long-lasting approaches in cardioprotection.
datePublished:2015-12-14T00:00:00Z
dateModified:2015-12-14T00:00:00Z
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Atherosclerosis
Cardioprotection
Cardiovascular disease
Endothelial permeability
Extracellular RNA
High-density lipoprotein
Hypoxia
Inflammation
Ischemia/reperfusion injury
Macrophage polarization
MicroRNAs
Mitochondria
Platelet dysfunction
Vascular biology
Cardiology
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headline:Meeting report from the 2nd International Symposium on New Frontiers in Cardiovascular Research. Protecting the cardiovascular system from ischemia: between bench and bedside
description:Recent advances in basic cardiovascular research as well as their translation into the clinical situation were the focus at the last âNew Frontiers in Cardiovascular Research meetingâ. Major topics included the characterization of new targets and procedures in cardioprotection, deciphering new players and inflammatory mechanisms in ischemic heart disease as well as uncovering microRNAs and other biomarkers as versatile and possibly causal factors in cardiovascular pathogenesis. Although a number of pathological situations such as ischemiaâreperfusion injury or atherosclerosis can be simulated and manipulated in diverse animal models, also to challenge new drugs for intervention, patient studies are the ultimate litmus test to obtain unequivocal information about the validity of biomedical concepts and their application in the clinics. Thus, the open and bidirectional exchange between bench and bedside is crucial to advance the field of ischemic heart disease with a particular emphasis of understanding long-lasting approaches in cardioprotection.
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Atherosclerosis
Cardioprotection
Cardiovascular disease
Endothelial permeability
Extracellular RNA
High-density lipoprotein
Hypoxia
Inflammation
Ischemia/reperfusion injury
Macrophage polarization
MicroRNAs
Mitochondria
Platelet dysfunction
Vascular biology
Cardiology
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