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Keywords {🔍}

rac, article, privacy, cookies, content, gtpases, information, publish, search, zheng, rho, signaling, access, chapter, data, log, journal, research, life, bosco, mulloy, cytoskeleton, cell, discover, signalling, author, springer, optional, personal, parties, policy, find, track, cellular, molecular, sciences, gtpase, trades, published, december, cite, explore, family, proliferation, conditions, institution, related, subjects, cincinnati, usa,

Topics {✒️}

month download article/chapter control cytoskeleton organization rho family privacy choices/manage cookies full article pdf gtpases rac1 author correspondence european economic area scope submit manuscript numerous pathological conditions hospital medical center conditions privacy policy accepting optional cookies related subjects aberrant cell signaling main content log journal finder publish rac1 gtpase gtpases article cellular cell proliferation check access instant access life sci privacy policy personal data information books a optional cookies manage preferences article number 370 article log signaling mechanisms ras signaling data protection essential cookies cookies skip subscription content similar content article cite institution subscribe journal publish article bosco usage analysis social media varying standards intracellular transducer deregulated expression activation patterns physiological functions

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         description:Rac1, a member of the Rho family of GTPases, is an intracellular transducer known to regulate multiple signaling pathways that control cytoskeleton organization, transcription, and cell proliferation. Deregulated expression or activation patterns of Rac1 can result in aberrant cell signaling and numerous pathological conditions. Here, we highlight the physiological functions and signaling mechanisms of Rac1 and their relevance to disease.
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