
DOI . ORG {
}
Title[redir]:
The role of tissue inhibitor of metalloproteinase-1 in specific aspects of cancer progression and reproduction | Journal of Neuro-Oncology
Description:
Tissue inhibitors of metalloproteinases (TIMPs) are specific inhibitors of the multi member family of matrix metalloproteinases (MMPs). Since MMP function is fundamental to events that require tissue remodelling, TIMPs regulate normal biological processes by inhibiting MMPs, and are of importance in pathological conditions. In this chapter we review evidence for the suppressive role of TIMP-1 in the malignant progression of cancer and of its regulatory function in controlling invasion during blastocyst implantation and development.
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Keywords {π}
google, scholar, cancer, inhibitor, tissue, metalloproteinases, cells, timp, article, khokha, invasion, expression, metastasis, inhibitors, tumor, cell, metalloproteinase, natl, role, waterhouse, matrix, factor, human, murine, res, metastatic, inst, membrane, privacy, cookies, content, journal, progression, collagenase, vitro, inhibition, melanoma, denhardt, mouse, growth, angiogenesis, werb, publish, search, access, extracellular, chambers, edwards, lala, lotan,
Topics {βοΈ}
ha-ras-transformed murine fibroblasts h-ras-transformed murine fibroblasts tumour cell lines b16-f10 melanoma cells antisense rna-induced reduction month download article/chapter chick yolk-sac membrane extracellular matrix-degrading metalloproteinases type iv collagenolysis fibroblast growth factor motility factor receptor privacy choices/manage cookies amnion invasionin vitro related subjects full article pdf ras-sensitive cells murine tissue inhibitors versatile extracellular regulators human amniotic membrane swiss 3t3 cells european economic area scope submit manuscript bird ccet al persky bet al stetler-stevenson wg host-mediated effectors d'amore pa pea3 binding sites identification metastatic behaviorin vivo natl cancer inst reconstituted basement membrane growth factor mouse reproductive tissues human amnion invasion require tissue remodelling multi member family cysteine proteinase cathepsin fibrosarcoma model derived growth-promoting activity neuro-oncology article mouse embryo cells mouse blastocyst outgrowth mouse trophoblast outgrowths expression correlates closely conditions privacy policy accepting optional cookies neuro-oncology aims natural protease inhibitors journal finder publish
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headline:The role of tissue inhibitor of metalloproteinase-1 in specific aspects of cancer progression and reproduction
description:Tissue inhibitors of metalloproteinases (TIMPs) are specific inhibitors of the multi member family of matrix metalloproteinases (MMPs). Since MMP function is fundamental to events that require tissue remodelling, TIMPs regulate normal biological processes by inhibiting MMPs, and are of importance in pathological conditions. In this chapter we review evidence for the suppressive role of TIMP-1 in the malignant progression of cancer and of its regulatory function in controlling invasion during blastocyst implantation and development.
datePublished:
dateModified:
pageStart:123
pageEnd:127
sameAs:https://doi.org/10.1007/BF01050418
keywords:
TIMP-1
metalloproteinases
metastasis
angiogenesis
implantation
Oncology
Neurology
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headline:The role of tissue inhibitor of metalloproteinase-1 in specific aspects of cancer progression and reproduction
description:Tissue inhibitors of metalloproteinases (TIMPs) are specific inhibitors of the multi member family of matrix metalloproteinases (MMPs). Since MMP function is fundamental to events that require tissue remodelling, TIMPs regulate normal biological processes by inhibiting MMPs, and are of importance in pathological conditions. In this chapter we review evidence for the suppressive role of TIMP-1 in the malignant progression of cancer and of its regulatory function in controlling invasion during blastocyst implantation and development.
datePublished:
dateModified:
pageStart:123
pageEnd:127
sameAs:https://doi.org/10.1007/BF01050418
keywords:
TIMP-1
metalloproteinases
metastasis
angiogenesis
implantation
Oncology
Neurology
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