
DOI . ORG {
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Title[redir]:
Evaluation of serum tumor markers in patients with advanced or recurrent breast cancer | Breast Cancer Research and Treatment
Description:
Serum CA15-3, CEA, and BCA225 concentrations were determined in 98 patients with advanced or recurrent breast cancer in an attempt to correlate elevation with clinical status. The rate of serum positivity was 68.4% (67/98), 55.1% (54/98), and 43.9% (43/98) for CA15-3, CEA, and BCA225, respectively. After a 4 weeksinterval, a 20% change of tumor marker concentration from the preceding assay correlated significantly with clinical findings. Significant elevation was predictive of new recurrence or tumor regrowth after complete remission, especially in patients with bone metastasis. The 20% change in concentration at 4 weeks was also useful in patients with tumor marker concentrations persistently beneath the cut-off level for positive. Serological evaluation of tumor markers in patients with advanced or recurrent breast cancer should seek to document 20% changes over a 4 week interval.
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Keywords {π}
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Topics {βοΈ}
serum tumor markers month download article/chapter breast cancer research tumour marker courses serum markers recurrent breast cancer privacy choices/manage cookies breast cancer treatments primary breast cancer metastasising breast cancer tumor markers toyokawa city hospital serum tumor marker circulating ca15-3 levels postoperative cea time breast cancer treatment serological evaluation toyota memorial hospital prognostic factors director hiroshi itoh breast cancer patients full article pdf director tetsuo hotta director kazuo shibata director hironori tanaka director katsumi nakamae european economic area sialyl-sugar residue bca225 concentrations conditions privacy policy tumor marker concentration monoclonal antibody reactive breast cancer breast cancer 7 director shoji karamatsu director koji matsuo accepting optional cookies check access instant access predictive journal finder publish cancer res 75 breast carcinoma cancer treatment cancer patient gastrointestinal cancer serum positivity related subjects tumour shunzo kobayashi
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