
DOI . ORG {
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Title[redir]:
Tobacco, alcohol intake, and diet in relation to adenocarcinoma of the esophagus and gastric cardia | Cancer Causes & Control
Description:
Little is known about the etiology of adenocarcinoma of the distal esophagus/cardia, a cancer which has increased in incidence in the United States over the last two decades. We analyzed data on smoking, alcohol use, dietary intake, and other factors obtained from 173 hospitalized males with adenocarcinoma of the distal esophagus/cardia (cases) and 4,544 hospitalized males with diseases not related to smoking and of other organ systems than the gastrointestinal tract (controls). Cases of squamous cell carcinoma of the esophagus (n=136) and adenocarcinoma of the distal stomach (n=122) were included as separate case groups. All subjects were interviewed in 28 hospitals in eight cities in the US between 1981 and 1990. After adjustment for covariates, the odds ratio (OR) for adenocarcinoma of the distal esophagus/cardia for current smokers was 2.3 (95 percent confidence interval [CI]=1.4β3.9) and that for ex-smokers was 1.9 (CI=1.2β3.0) relative to never-smokers. The OR for drinkers of four or more ounces of whiskey-equivalents of alcohol per day (relative to those consuming less than one drink per week) was 2.3 (CI=1.3β4.3). Intakes of total fat and vitamin A from animal sources were significant risk factors and fiber intake was associated inversely with adenocarcinoma of the distal esophagus/cardia. Although the number of female cases of adenocarcinoma of the distal esophagus/cardia was small (n=21), significant associations were observed for smoking and alcohol.
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cancer, google, scholar, adenocarcinoma, esophagus, gastric, alcohol, cardia, article, study, stomach, smoking, factors, esophageal, epidemiology, distal, research, tobacco, intake, kabat, incidence, risk, privacy, cookies, content, control, diet, wynder, esophaguscardia, access, casecontrol, data, publish, search, relation, united, states, dietary, cases, oesophageal, macdonald, int, res, medicine, social, information, log, journal, related, subjects,
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body mass index age-period-cohort effects month download article/chapter blot wj significant risk factors united states lung cancer risk selected environmental factors dietary factors privacy choices/manage cookies risk factors oesophageal cancer studies center grant ca17613 full article pdf esophageal cancer owing gastrointestinal tract american health foundation check access instant access european economic area separate case groups los angeles county government printing office sas/stat user' albert einstein college case-control study conditions privacy policy dietary intake oesophageal cancer dr kabat accepting optional cookies squamous cell carcinoma esophageal adenocarcinoma survival factors obtained etiological factors main content log article cancer article kabat journal finder publish related subjects sas institute esophageal cancer tobacco smoking usage analysis distal esophagus/cardia stomach cancers attributable epidemiological research gastric cardia article log kabat gc
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headline:Tobacco, alcohol intake, and diet in relation to adenocarcinoma of the esophagus and gastric cardia
description:Little is known about the etiology of adenocarcinoma of the distal esophagus/cardia, a cancer which has increased in incidence in the United States over the last two decades. We analyzed data on smoking, alcohol use, dietary intake, and other factors obtained from 173 hospitalized males with adenocarcinoma of the distal esophagus/cardia (cases) and 4,544 hospitalized males with diseases not related to smoking and of other organ systems than the gastrointestinal tract (controls). Cases of squamous cell carcinoma of the esophagus (n=136) and adenocarcinoma of the distal stomach (n=122) were included as separate case groups. All subjects were interviewed in 28 hospitals in eight cities in the US between 1981 and 1990. After adjustment for covariates, the odds ratio (OR) for adenocarcinoma of the distal esophagus/cardia for current smokers was 2.3 (95 percent confidence interval [CI]=1.4β3.9) and that for ex-smokers was 1.9 (CI=1.2β3.0) relative to never-smokers. The OR for drinkers of four or more ounces of whiskey-equivalents of alcohol per day (relative to those consuming less than one drink per week) was 2.3 (CI=1.3β4.3). Intakes of total fat and vitamin A from animal sources were significant risk factors and fiber intake was associated inversely with adenocarcinoma of the distal esophagus/cardia. Although the number of female cases of adenocarcinoma of the distal esophagus/cardia was small (n=21), significant associations were observed for smoking and alcohol.
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body mass index
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smoking
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headline:Tobacco, alcohol intake, and diet in relation to adenocarcinoma of the esophagus and gastric cardia
description:Little is known about the etiology of adenocarcinoma of the distal esophagus/cardia, a cancer which has increased in incidence in the United States over the last two decades. We analyzed data on smoking, alcohol use, dietary intake, and other factors obtained from 173 hospitalized males with adenocarcinoma of the distal esophagus/cardia (cases) and 4,544 hospitalized males with diseases not related to smoking and of other organ systems than the gastrointestinal tract (controls). Cases of squamous cell carcinoma of the esophagus (n=136) and adenocarcinoma of the distal stomach (n=122) were included as separate case groups. All subjects were interviewed in 28 hospitals in eight cities in the US between 1981 and 1990. After adjustment for covariates, the odds ratio (OR) for adenocarcinoma of the distal esophagus/cardia for current smokers was 2.3 (95 percent confidence interval [CI]=1.4β3.9) and that for ex-smokers was 1.9 (CI=1.2β3.0) relative to never-smokers. The OR for drinkers of four or more ounces of whiskey-equivalents of alcohol per day (relative to those consuming less than one drink per week) was 2.3 (CI=1.3β4.3). Intakes of total fat and vitamin A from animal sources were significant risk factors and fiber intake was associated inversely with adenocarcinoma of the distal esophagus/cardia. Although the number of female cases of adenocarcinoma of the distal esophagus/cardia was small (n=21), significant associations were observed for smoking and alcohol.
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Alcohol
body mass index
dietary factors
esophageal cancer
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United States
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Epidemiology
Hematology
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