DOI . ORG {}

Analyzed Page
Matching Content Categories
CMS
Monthly Traffic Estimate
How Does Doi.org Make Money
Keywords
Topics
Questions
Schema
External Links
Analytics And Tracking
Libraries
Hosting Providers
CDN Services

We began analyzing https://link.springer.com/protocol/10.1007/978-1-61779-201-4_19, but it redirected us to https://link.springer.com/protocol/10.1007/978-1-61779-201-4_19. The analysis below is for the second page.

Title[redir]:
Genome-Wide Epigenetic Analysis of Human Pluripotent Stem Cells by ChIP and ChIP-Seq | SpringerLink
Description:
Chromatin immunoprecipitation (ChIP) is used to evaluate the interaction of proteins and genomic DNA. In eukaryotic cells, the DNA is highly compacted with the evolutionarily conserved histone proteins (which together with DNA form the nucleosome) and other...

Matching Content Categories {📚}

Science
Education
Telecommunications

Content Management System {📝}

What CMS is doi.org built with?

Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Doi.org Make Money? {💸}

We can't tell how the site generates income.

Not all websites focus on profit; some are designed to educate, connect people, or share useful tools. People create websites for numerous reasons. And this could be one such example. Doi.org might be making money, but it's not detectable how they're doing it.

Keywords {🔍}

stem, cells, cell, histone, google, scholar, article, cas, pubmed, human, pluripotent, protocol, research, genomewide, chromatin, modifications, chapter, privacy, cookies, content, information, publish, epigenetic, chip, rice, biology, proteins, transcription, embryonic, nature, analysis, journal, search, chipseq, dna, download, california, usa, springer, usd, personal, data, including, log, hitchler, judd, book, methods, molecular, genomic,

Topics {✒️}

genome-wide epigenetic analysis month download article/chapter transcription factor-binding sites embryonic stem cells distinct dna-templated process high-throughput dna sequencing stem cell research genome-wide scale genome-wide mapping genome-wide maps privacy choices/manage cookies integrative genomic analysis lineage-committed cells pluripotent cell lines device instant download unraveling epigenetic regulation humana press human genome stem cell biology stem cells early mouse embryo high-resolution profiling journal finder publish european economic area dissecting direct reprogramming editor information editors applied technology developmen chip-seq protocol conditions privacy policy specific amino acids edythe broad center accepting optional cookies yield important insights author information authors protocol usd 49 specific histone modifications library construction methods precise genomic location usage analysis online epigenetic regulation protocol cite chip-seq experiments cell science main content log including transcription epigenetic regulators eukaryotic cells million cells protocol hitchler

Questions {❓}

(2003) Phosphorylation of serine 10 in histone H3, what for?
(2004) SUMO and ubiquitin in the nucleus: different functions, similar mechanisms?

Schema {🗺️}

ScholarlyArticle:
      headline:Genome-Wide Epigenetic Analysis of Human Pluripotent Stem Cells by ChIP and ChIP-Seq
      pageEnd:267
      pageStart:253
      image:https://media.springernature.com/w153/springer-static/cover/book/978-1-61779-201-4.jpg
      genre:
         Springer Protocols
      isPartOf:
         name:Human Pluripotent Stem Cells
         isbn:
            978-1-61779-201-4
            978-1-61779-200-7
         type:Book
      publisher:
         name:Humana Press
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Michael J. Hitchler
            affiliation:
                  name:University of Southern California, Keck School of Medicine
                  address:
                     name:Department of Biochemistry and Molecular Biology, University of Southern California, Keck School of Medicine, Los Angeles, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Judd C. Rice
            affiliation:
                  name:University of Southern California, Keck School of Medicine
                  address:
                     name:Department of Biochemistry and Molecular Biology, University of Southern California, Keck School of Medicine, Los Angeles, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      keywords:chromatin immunoprecipitation, ChIP, ChIP-Seq, histone methylation, human embryonic stem cells, chromatin, epigenome
      description:Chromatin immunoprecipitation (ChIP) is used to evaluate the interaction of proteins and genomic DNA. In eukaryotic cells, the DNA is highly compacted with the evolutionarily conserved histone proteins (which together with DNA form the nucleosome) and other chromosomal-associated proteins to form the chromatin structure. Chromatin structure is dynamically regulated by several mechanisms including transcription factor binding and various posttranslational modifications of the histone proteins. The chromatin structure can be affected by environmental factors, such as those that induce differentiation or promote self-renewal in stem cells. Using very specific antibodies, one can evaluate the specific amino acids within the histones and each one of these modifications is associated with a distinct DNA-templated process, including transcription. Therefore, determining the location of transcription factors and histone modifications can yield important insights into the DNA-associated activities that are occurring at that particular region of the genome at that time. ChIP followed by high-throughput DNA sequencing (ChIP-Seq) provides a means to rapidly determine the precise genomic location of transcription factor binding sites and histone modifications on a genome-wide scale. Genome-wide mapping of histone modifications and chromatin-associated proteins have already begun to reveal the mechanisms responsible for regulating the pattern of gene expression in mouse embryonic stem cells. However, similar studies in human embryonic stem cells are currently lacking due to the difficulty in obtaining the large number of purified cells typically required for ChIP and ChIP-Seq experiments. Here, we describe a detailed method for determining the locations of specific histone modifications using only one million cells.
      datePublished:2011
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
      context:https://schema.org
Book:
      name:Human Pluripotent Stem Cells
      isbn:
         978-1-61779-201-4
         978-1-61779-200-7
Organization:
      name:Humana Press
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:University of Southern California, Keck School of Medicine
      address:
         name:Department of Biochemistry and Molecular Biology, University of Southern California, Keck School of Medicine, Los Angeles, USA
         type:PostalAddress
      name:University of Southern California, Keck School of Medicine
      address:
         name:Department of Biochemistry and Molecular Biology, University of Southern California, Keck School of Medicine, Los Angeles, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Michael J. Hitchler
      affiliation:
            name:University of Southern California, Keck School of Medicine
            address:
               name:Department of Biochemistry and Molecular Biology, University of Southern California, Keck School of Medicine, Los Angeles, USA
               type:PostalAddress
            type:Organization
      name:Judd C. Rice
      affiliation:
            name:University of Southern California, Keck School of Medicine
            address:
               name:Department of Biochemistry and Molecular Biology, University of Southern California, Keck School of Medicine, Los Angeles, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Biochemistry and Molecular Biology, University of Southern California, Keck School of Medicine, Los Angeles, USA
      name:Department of Biochemistry and Molecular Biology, University of Southern California, Keck School of Medicine, Los Angeles, USA
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(90)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js

Emails and Hosting {✉️}

Mail Servers:

mx.zoho.eu
mx2.zoho.eu
mx3.zoho.eu

Name Servers:

josh.ns.cloudflare.com
zita.ns.cloudflare.com

CDN Services {📦}

Pbgrd

4.23s.