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DOI . ORG {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
  8. Questions
  9. Schema
  10. External Links
  11. Analytics And Tracking
  12. Libraries
  13. Hosting Providers
  14. CDN Services

We began analyzing https://link.springer.com/protocol/10.1007/978-1-4939-6952-4_5, but it redirected us to https://link.springer.com/protocol/10.1007/978-1-4939-6952-4_5. The analysis below is for the second page.

Title[redir]:
Evolving Relevance of Neuroproteomics in Alzheimer’s Disease | SpringerLink
Description:
Substantial progress in the understanding of the biology of Alzheimer’s disease (AD) has been achieved over the past decades. The early detection and diagnosis of AD and other age-related neurodegenerative diseases, however, remain a challenging scientific...

Matching Content Categories {📚}

  • Education
  • Science
  • Health & Fitness

Content Management System {📝}

What CMS is doi.org built with?

Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

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How Does Doi.org Make Money? {💸}

We don't see any clear sign of profit-making.

Not every website is profit-driven; some are created to spread information or serve as an online presence. Websites can be made for many reasons. This could be one of them. Doi.org might be making money, but it's not detectable how they're doing it.

Keywords {🔍}

pubmed, google, scholar, article, cas, alzheimers, disease, biomarkers, fluid, central, cerebrospinal, proteomics, alzheimer, plasma, hampel, lista, dis, research, diagnosis, proteome, biology, biomarker, zetterberg, blennow, biological, res, med, protein, rev, neurol, obryant, early, systems, amyloid, bloodbased, neuroproteomics, protocol, detection, discovery, markers, mol, dement, clinical, paris, portelius, molecular, cognitive, proteomic, data, neurodegenerative,

Topics {✒️}

month download article/chapter exploratory high-throughput technologies post-dural puncture headache post-lumbar puncture headache mass spectrometry-based analyses amyloid beta-related mechanisms beta-amyloid peptide signatures craig-schapiro blood-based screening tool serum protein-based algorithm omics-based biomarkers discovery mass spectrometry-based proteomics axa research fund blood-based protein biomarkers systems-level disease involving blood-based biomarker studies amyloid-β peptides detection age-related neurodegenerative diseases proteome-based plasma biomarkers simone lista ph privacy choices/manage cookies de la maladie device instant download amyloid beta peptides systems biology paradigm teipel sj multiple analytical groups including mass spectrometry amyloid cascade hypothesis blood-based algorithm de leon mj département de neurologie immunoprecipitation–mass spectrometry swedish research council multivariate protein signatures institut du cerveau plasma protein profiling proteomic biomarker discovery med clin north prognostic fluid biomarker plasma protein biomarkers effective exploratory discovery regional brain volumes author information authors editor information editors fondation université pierre blood-based biomarkers rigorous computational modelling deciphering complex mechanisms therapeutic gordian knot

Questions {❓}

  • Evans C, Noirel J, Ow SY et al (2012) An insight into iTRAQ: where do we stand now?
  • Karran E, Hardy J (2014) Antiamyloid therapy for Alzheimer’s disease—are we on the right road?
  • Morris JK, Honea RA, Vidoni ED et al (2014) Is Alzheimer’s disease a systemic disease?

Schema {🗺️}

ScholarlyArticle:
      headline:Evolving Relevance of Neuroproteomics in Alzheimer’s Disease
      pageEnd:115
      pageStart:101
      image:https://media.springernature.com/w153/springer-static/cover/book/978-1-4939-6952-4.jpg
      genre:
         Springer Protocols
      isPartOf:
         name:Neuroproteomics
         isbn:
            978-1-4939-6952-4
            978-1-4939-6950-0
         type:Book
      publisher:
         name:Springer New York
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Simone Lista
            affiliation:
                  name:AXA Research Fund & UPMC Chair
                  address:
                     name:AXA Research Fund & UPMC Chair, Paris, France
                     type:PostalAddress
                  type:Organization
                  name:Sorbonne Universités, Université Pierre et Marie Curie (UPMC) Paris 06, Inserm, CNRS, Institut du cerveau et dela moelle (ICM), Département de Neurologie, Institut de la Mémoire et de la Maladie d’Alzheimer (IM2A), HôpitalPitié-Salpêtrière
                  address:
                     name:Sorbonne Universités, Université Pierre et Marie Curie (UPMC) Paris 06, Inserm, CNRS, Institut du cerveau et dela moelle (ICM), Département de Neurologie, Institut de la Mémoire et de la Maladie d’Alzheimer (IM2A), HôpitalPitié-Salpêtrière, Paris, France
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Henrik Zetterberg
            affiliation:
                  name:The Sahlgrenska Academy at the University of Gothenburg
                  address:
                     name:Clinical Neurochemistry Laboratory, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden
                     type:PostalAddress
                  type:Organization
                  name:UCL Institute of Neurology
                  address:
                     name:Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Sid E. O’Bryant
            affiliation:
                  name:University of North Texas Health Science Center
                  address:
                     name:Institute for Healthy Aging, University of North Texas Health Science Center, Fort Worth, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Kaj Blennow
            affiliation:
                  name:The Sahlgrenska Academy at the University of Gothenburg
                  address:
                     name:Clinical Neurochemistry Laboratory, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden
                     type:PostalAddress
                  type:Organization
                  name:The Torsten Söderberg Professorship in Medicine at the Royal Swedish Academy of Sciences
                  address:
                     name:The Torsten Söderberg Professorship in Medicine at the Royal Swedish Academy of Sciences, Stockholm, Sweden
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Harald Hampel
            affiliation:
                  name:AXA Research Fund & UPMC Chair
                  address:
                     name:AXA Research Fund & UPMC Chair, Paris, France
                     type:PostalAddress
                  type:Organization
                  name:Sorbonne Universités, Université Pierre et Marie Curie, Paris 06, Institut de la Mémoire et de la Maladie d’Alzheimer (IM2A) & Institut du Cerveau et de la Moelle Épinière (ICM), Paris, France; Département de Neurologie, Hôpital de la Pitié-Salpêtrière
                  address:
                     name:Sorbonne Universités, Université Pierre et Marie Curie, Paris 06, Institut de la Mémoire et de la Maladie d’Alzheimer (IM2A) & Institut du Cerveau et de la Moelle Épinière (ICM), Paris, France; Département de Neurologie, Hôpital de la Pitié-Salpêtrière, Paris, France
                     type:PostalAddress
                  type:Organization
            type:Person
      keywords:Alzheimer’s disease, Systems biology , Omics sciences, Proteomics, Neuroproteomics, Biomarkers, Mass spectrometry, Cerebrospinal fluid, Blood, Plasma/serum, Detection/diagnosis
      description:Substantial progress in the understanding of the biology of Alzheimer’s disease (AD) has been achieved over the past decades. The early detection and diagnosis of AD and other age-related neurodegenerative diseases, however, remain a challenging scientific frontier. Therefore, the comprehensive discovery (relating to all individual, converging or diverging biochemical disease mechanisms), development, validation, and qualification of standardized biological markers with diagnostic and prognostic functions with a precise performance profile regarding specificity, sensitivity, and positive and negative predictive value are warranted. Methodological innovations in the area of exploratory high-throughput technologies, such as sequencing, microarrays, and mass spectrometry-based analyses of proteins/peptides, have led to the generation of large global molecular datasets from a multiplicity of biological systems, such as biological fluids, cells, tissues, and organs. Such methodological progress has shifted the attention to the execution of hypothesis-independent comprehensive exploratory analyses (opposed to the classical hypothesis-driven candidate approach), with the aim of fully understanding the biological systems in physiology and disease as a whole. The systems biology paradigm integrates experimental biology with accurate and rigorous computational modelling to describe and foresee the dynamic features of biological systems. The use of dynamically evolving technological platforms, including mass spectrometry, in the area of proteomics has enabled to rush the process of biomarker discovery and validation for refining significantly the diagnosis of AD. Currently, proteomics—which is part of the systems biology paradigm—is designated as one of the dominant matured sciences needed for the effective exploratory discovery of prospective biomarker candidates expected to play an effective role in aiding the early detection, diagnosis, prognosis, and therapy development in AD.
      datePublished:2017
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Book:
      name:Neuroproteomics
      isbn:
         978-1-4939-6952-4
         978-1-4939-6950-0
Organization:
      name:Springer New York
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:AXA Research Fund & UPMC Chair
      address:
         name:AXA Research Fund & UPMC Chair, Paris, France
         type:PostalAddress
      name:Sorbonne Universités, Université Pierre et Marie Curie (UPMC) Paris 06, Inserm, CNRS, Institut du cerveau et dela moelle (ICM), Département de Neurologie, Institut de la Mémoire et de la Maladie d’Alzheimer (IM2A), HôpitalPitié-Salpêtrière
      address:
         name:Sorbonne Universités, Université Pierre et Marie Curie (UPMC) Paris 06, Inserm, CNRS, Institut du cerveau et dela moelle (ICM), Département de Neurologie, Institut de la Mémoire et de la Maladie d’Alzheimer (IM2A), HôpitalPitié-Salpêtrière, Paris, France
         type:PostalAddress
      name:The Sahlgrenska Academy at the University of Gothenburg
      address:
         name:Clinical Neurochemistry Laboratory, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden
         type:PostalAddress
      name:UCL Institute of Neurology
      address:
         name:Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK
         type:PostalAddress
      name:University of North Texas Health Science Center
      address:
         name:Institute for Healthy Aging, University of North Texas Health Science Center, Fort Worth, USA
         type:PostalAddress
      name:The Sahlgrenska Academy at the University of Gothenburg
      address:
         name:Clinical Neurochemistry Laboratory, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden
         type:PostalAddress
      name:The Torsten Söderberg Professorship in Medicine at the Royal Swedish Academy of Sciences
      address:
         name:The Torsten Söderberg Professorship in Medicine at the Royal Swedish Academy of Sciences, Stockholm, Sweden
         type:PostalAddress
      name:AXA Research Fund & UPMC Chair
      address:
         name:AXA Research Fund & UPMC Chair, Paris, France
         type:PostalAddress
      name:Sorbonne Universités, Université Pierre et Marie Curie, Paris 06, Institut de la Mémoire et de la Maladie d’Alzheimer (IM2A) & Institut du Cerveau et de la Moelle Épinière (ICM), Paris, France; Département de Neurologie, Hôpital de la Pitié-Salpêtrière
      address:
         name:Sorbonne Universités, Université Pierre et Marie Curie, Paris 06, Institut de la Mémoire et de la Maladie d’Alzheimer (IM2A) & Institut du Cerveau et de la Moelle Épinière (ICM), Paris, France; Département de Neurologie, Hôpital de la Pitié-Salpêtrière, Paris, France
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Simone Lista
      affiliation:
            name:AXA Research Fund & UPMC Chair
            address:
               name:AXA Research Fund & UPMC Chair, Paris, France
               type:PostalAddress
            type:Organization
            name:Sorbonne Universités, Université Pierre et Marie Curie (UPMC) Paris 06, Inserm, CNRS, Institut du cerveau et dela moelle (ICM), Département de Neurologie, Institut de la Mémoire et de la Maladie d’Alzheimer (IM2A), HôpitalPitié-Salpêtrière
            address:
               name:Sorbonne Universités, Université Pierre et Marie Curie (UPMC) Paris 06, Inserm, CNRS, Institut du cerveau et dela moelle (ICM), Département de Neurologie, Institut de la Mémoire et de la Maladie d’Alzheimer (IM2A), HôpitalPitié-Salpêtrière, Paris, France
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Henrik Zetterberg
      affiliation:
            name:The Sahlgrenska Academy at the University of Gothenburg
            address:
               name:Clinical Neurochemistry Laboratory, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden
               type:PostalAddress
            type:Organization
            name:UCL Institute of Neurology
            address:
               name:Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK
               type:PostalAddress
            type:Organization
      name:Sid E. O’Bryant
      affiliation:
            name:University of North Texas Health Science Center
            address:
               name:Institute for Healthy Aging, University of North Texas Health Science Center, Fort Worth, USA
               type:PostalAddress
            type:Organization
      name:Kaj Blennow
      affiliation:
            name:The Sahlgrenska Academy at the University of Gothenburg
            address:
               name:Clinical Neurochemistry Laboratory, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden
               type:PostalAddress
            type:Organization
            name:The Torsten Söderberg Professorship in Medicine at the Royal Swedish Academy of Sciences
            address:
               name:The Torsten Söderberg Professorship in Medicine at the Royal Swedish Academy of Sciences, Stockholm, Sweden
               type:PostalAddress
            type:Organization
      name:Harald Hampel
      affiliation:
            name:AXA Research Fund & UPMC Chair
            address:
               name:AXA Research Fund & UPMC Chair, Paris, France
               type:PostalAddress
            type:Organization
            name:Sorbonne Universités, Université Pierre et Marie Curie, Paris 06, Institut de la Mémoire et de la Maladie d’Alzheimer (IM2A) & Institut du Cerveau et de la Moelle Épinière (ICM), Paris, France; Département de Neurologie, Hôpital de la Pitié-Salpêtrière
            address:
               name:Sorbonne Universités, Université Pierre et Marie Curie, Paris 06, Institut de la Mémoire et de la Maladie d’Alzheimer (IM2A) & Institut du Cerveau et de la Moelle Épinière (ICM), Paris, France; Département de Neurologie, Hôpital de la Pitié-Salpêtrière, Paris, France
               type:PostalAddress
            type:Organization
PostalAddress:
      name:AXA Research Fund & UPMC Chair, Paris, France
      name:Sorbonne Universités, Université Pierre et Marie Curie (UPMC) Paris 06, Inserm, CNRS, Institut du cerveau et dela moelle (ICM), Département de Neurologie, Institut de la Mémoire et de la Maladie d’Alzheimer (IM2A), HôpitalPitié-Salpêtrière, Paris, France
      name:Clinical Neurochemistry Laboratory, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden
      name:Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK
      name:Institute for Healthy Aging, University of North Texas Health Science Center, Fort Worth, USA
      name:Clinical Neurochemistry Laboratory, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden
      name:The Torsten Söderberg Professorship in Medicine at the Royal Swedish Academy of Sciences, Stockholm, Sweden
      name:AXA Research Fund & UPMC Chair, Paris, France
      name:Sorbonne Universités, Université Pierre et Marie Curie, Paris 06, Institut de la Mémoire et de la Maladie d’Alzheimer (IM2A) & Institut du Cerveau et de la Moelle Épinière (ICM), Paris, France; Département de Neurologie, Hôpital de la Pitié-Salpêtrière, Paris, France
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(431)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Clipboard.js

Emails and Hosting {✉️}

Mail Servers:

  • mx.zoho.eu
  • mx2.zoho.eu
  • mx3.zoho.eu

Name Servers:

  • josh.ns.cloudflare.com
  • zita.ns.cloudflare.com

CDN Services {📦}

  • Pbgrd

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