
DOI . ORG {
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Title[redir]:
A Randomized Phase IIb Study of Mavrilimumab and Golimumab in Rheumatoid Arthritis - Weinblatt - 2018 - Arthritis & Rheumatology - Wiley Online Library
Description:
Objective This 24-week, phase IIb, double-blind study was undertaken to evaluate the efficacy and safety of mavrilimumab (a monoclonal antibody to granulocyte–macrophage colony-stimulating factor re...
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Keywords {🔍}
patients, mavrilimumab, week, study, treatment, golimumab, response, group, acr, antitnfir, population, weeks, dmardir, dascrp, percentage, improvement, score, dosage, efficacy, data, baseline, safety, antitnf, disease, rates, inadequate, history, compared, crp, higher, randomized, received, clinical, agents, groups, haq, receiving, stratum, observed, pulmonary, drug, difference, phase, activity, rate, figure, results, reported, tnf, based,
Topics {✒️}
granulocyte–macrophage colony-stimulating factor article information search anti–tumor necrosis factor long-term ole study anti-tnf–ir stratum compared disease-modifying antirheumatic drugs anti-tnf–ir ra population c-reactive protein level anti-tnf–ir stratum prior anti-tnf failures full access previous anti-tnf failures anti-tnf–ir group anti-tnf–ir population anti-tnf–ir strata prior anti-tnf treatment anti–gm-csf autoantibodies privacy policy skip treatment-emergent adverse events dmard-ir stratum recruited open-label extension c-reactive protein health assessment questionnaire anti-tnf agents 2 anti-tnf agents 2 anti-tnf failures treatment visit rheumatoid arthritis michael anti-tnf–ir article content skip biologic agent–experienced patients anti-tnf stratum received research funding anti-tnf failure anti-tnf agent cell costimulation [abatacept] tnf antagonist failures rheumatoid factor–positive gm-csf signaling gm-csf receptor astrazeneca/medimmune study group interleukin-6 receptor [tocilizumab] nonsteroidal antiinflammatory drugs acr70 response rates reducing cell numbers clinical trials good clinical practice antidrug antibody response higher response rates higher disease activity
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- How much profit does https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/action/getFTRLinkout?url=http%3A%2F%2Fscholar.google.com%2Fscholar_lookup%3Fhl%3Den%26volume%3D48%26publication_year%3D2003%26pages%3D35-45%26journal%3DArthritis%2BRheum%26author%3DME%2BWeinblatt%26author%3DEC%2BKeystone%26author%3DDE%2BFurst%26author%3DLW%2BMoreland%26author%3DMH%2BWeisman%26author%3DCA%2BBirbara%26title%3DAdalimumab%252C%2Ba%2Bfully%2Bhuman%2Banti%25E2%2580%2593tumor%2Bnecrosis%2Bfactor%2B%25CE%25B1%2Bmonoclonal%2Bantibody%252C%2Bfor%2Bthe%2Btreatment%2Bof%2Brheumatoid%2Barthritis%2Bin%2Bpatients%2Btaking%2Bconcomitant%2Bmethotrexate%253A%2Bthe%2BARMADA%2Btrial&doi=10.1002%2Fart.40323&doiOfLink=10.1002%2Fart.10697&linkType=gs&linkLocation=Reference&linkSource=FULL_TEXT generate?
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- How much revenue does https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/servlet/linkout?suffix=null&dbid=128&doi=10.1002%2Fart.40323&key=000078318700001&getFTLinkType=true&doiForPubOfPage=10.1002%2Fart.40323&refDoi=10.1056%2FNEJM199901283400401&linkType=ISI&linkSource=FULL_TEXT&linkLocation=Reference bring in?
- What are the total earnings of https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/action/getFTRLinkout?url=http%3A%2F%2Fscholar.google.com%2Fscholar_lookup%3Fhl%3Den%26volume%3D340%26publication_year%3D1999%26pages%3D253-9%26journal%3DN%2BEngl%2BJ%2BMed%26author%3DME%2BWeinblatt%26author%3DJM%2BKremer%26author%3DAD%2BBankhurst%26author%3DKJ%2BBulpitt%26author%3DRM%2BFleischmann%26author%3DRI%2BFox%26title%3DA%2Btrial%2Bof%2Betanercept%252C%2Ba%2Brecombinant%2Btumor%2Bnecrosis%2Bfactor%2Breceptor%253AFc%2Bfusion%2Bprotein%252C%2Bin%2Bpatients%2Bwith%2Brheumatoid%2Barthritis%2Breceiving%2Bmethotrexate&doi=10.1002%2Fart.40323&doiOfLink=10.1056%2FNEJM199901283400401&linkType=gs&linkLocation=Reference&linkSource=FULL_TEXT?
- See how much https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/servlet/linkout?suffix=null&dbid=32&doi=10.1002%2Fart.40323&key=1%3ASTN%3A280%3ADyaK2M3pvVSmtA%253D%253D&getFTLinkType=true&doiForPubOfPage=10.1002%2Fart.40323&refDoi=10.1002%2Fart.1780380602&linkType=COI&linkSource=FULL_TEXT&linkLocation=Reference makes per month
- How much does https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/servlet/linkout?suffix=null&dbid=8&doi=10.1002%2Fart.40323&key=7779114&getFTLinkType=true&doiForPubOfPage=10.1002%2Fart.40323&refDoi=10.1002%2Fart.1780380602&linkType=PMID&linkSource=FULL_TEXT&linkLocation=Reference bring in each month?
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- How much does https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/action/getFTRLinkout?url=http%3A%2F%2Fscholar.google.com%2Fscholar_lookup%3Fhl%3Den%26volume%3D38%26publication_year%3D1995%26pages%3D727-35%26journal%3DArthritis%2BRheum%26author%3DDT%2BFelson%26author%3DJJ%2BAnderson%26author%3DM%2BBoers%26author%3DC%2BBombardier%26author%3DD%2BFurst%26author%3DC%2BGoldsmith%26title%3DAmerican%2BCollege%2Bof%2BRheumatology%2Bpreliminary%2Bdefinition%2Bof%2Bimprovement%2Bin%2Brheumatoid%2Barthritis&doi=10.1002%2Fart.40323&doiOfLink=10.1002%2Fart.1780380602&linkType=gs&linkLocation=Reference&linkSource=FULL_TEXT gross monthly?
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- How much income does https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/servlet/linkout?suffix=null&dbid=8&doi=10.1002%2Fart.40323&key=21632797&getFTLinkType=true&doiForPubOfPage=10.1002%2Fart.40323&refDoi=10.1183%2F09059180.00001311&linkType=PMID&linkSource=FULL_TEXT&linkLocation=Reference have?
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- How much does https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/servlet/linkout?suffix=null&dbid=8&doi=10.1002%2Fart.40323&key=18551202&getFTLinkType=true&doiForPubOfPage=10.1002%2Fart.40323&refDoi=10.1155%2F2008%2F528948&linkType=PMID&linkSource=FULL_TEXT&linkLocation=Reference gross monthly?
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- What's the financial intake of https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/action/getFTRLinkout?url=http%3A%2F%2Fscholar.google.com%2Fscholar_lookup%3Fhl%3Den%26volume%3D15%26publication_year%3D2008%26pages%3D203-10%26journal%3DCan%2BRespir%2BJ%26author%3DSC%2BJuvet%26author%3DD%2BHwang%26author%3DTK%2BWaddell%26author%3DGP%2BDowney%26title%3DRare%2Blung%2Bdisease%2BII%253A%2Bpulmonary%2Balveolar%2Bproteinosis&doi=10.1002%2Fart.40323&doiOfLink=10.1155%2F2008%2F528948&linkType=gs&linkLocation=Reference&linkSource=FULL_TEXT?
- https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/servlet/linkout?suffix=null&dbid=32&doi=10.1002%2Fart.40323&key=1%3ASTN%3A280%3ADyaL3c7ltlGlsQ%253D%253D&getFTLinkType=true&doiForPubOfPage=10.1002%2Fart.40323&refDoi=10.1002%2Fart.1780230202&linkType=COI&linkSource=FULL_TEXT&linkLocation=Reference's financial summary
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- How much does https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/servlet/linkout?suffix=null&dbid=128&doi=10.1002%2Fart.40323&key=A1980JF16100001&getFTLinkType=true&doiForPubOfPage=10.1002%2Fart.40323&refDoi=10.1002%2Fart.1780230202&linkType=ISI&linkSource=FULL_TEXT&linkLocation=Reference rake in every month?
- What's the income of https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/action/getFTRLinkout?url=http%3A%2F%2Fscholar.google.com%2Fscholar_lookup%3Fhl%3Den%26volume%3D23%26publication_year%3D1980%26pages%3D137-45%26journal%3DArthritis%2BRheum%26author%3DJF%2BFries%26author%3DP%2BSpitz%26author%3DRG%2BKraines%26author%3DHR%2BHolman%26title%3DMeasurement%2Bof%2Bpatient%2Boutcome%2Bin%2Barthritis&doi=10.1002%2Fart.40323&doiOfLink=10.1002%2Fart.1780230202&linkType=gs&linkLocation=Reference&linkSource=FULL_TEXT?
- Revenue of https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/servlet/linkout?suffix=null&dbid=32&doi=10.1002%2Fart.40323&key=1%3ASTN%3A280%3ADyaK287jtlamuw%253D%253D&getFTLinkType=true&doiForPubOfPage=10.1002%2Fart.40323&refDoi=10.1002%2Fart.1780390105&linkType=COI&linkSource=FULL_TEXT&linkLocation=Reference
- What's the revenue for https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/servlet/linkout?suffix=null&dbid=8&doi=10.1002%2Fart.40323&key=8546736&getFTLinkType=true&doiForPubOfPage=10.1002%2Fart.40323&refDoi=10.1002%2Fart.1780390105&linkType=PMID&linkSource=FULL_TEXT&linkLocation=Reference?
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- How much does https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/action/getFTRLinkout?url=http%3A%2F%2Fscholar.google.com%2Fscholar_lookup%3Fhl%3Den%26volume%3D39%26publication_year%3D1996%26pages%3D34-40%26journal%3DArthritis%2BRheum%26author%3DAM%2BVan%2BGestel%26author%3DML%2BPrevoo%26author%3DMA%2BHof%26author%3DMH%2BRijswijk%26author%3DLB%2BPutte%26author%3DPL%2BRiel%26title%3DDevelopment%2Band%2Bvalidation%2Bof%2Bthe%2BEuropean%2BLeague%2BAgainst%2BRheumatism%2Bresponse%2Bcriteria%2Bfor%2Brheumatoid%2Barthritis%253A%2Bcomparison%2Bwith%2Bthe%2Bpreliminary%2BAmerican%2BCollege%2Bof%2BRheumatology%2Band%2Bthe%2BWorld%2BHealth%2BOrganization%252FInternational%2BLeague%2BAgainst%2BRheumatism%2Bcriteria&doi=10.1002%2Fart.40323&doiOfLink=10.1002%2Fart.1780390105&linkType=gs&linkLocation=Reference&linkSource=FULL_TEXT net monthly?
- How much profit does https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/servlet/linkout?suffix=null&dbid=32&doi=10.1002%2Fart.40323&key=1%3ACAS%3A528%3ADC%252BD2MXkt1CjsLY%253D&getFTLinkType=true&doiForPubOfPage=10.1002%2Fart.40323&refDoi=10.1186%2Far1740&linkType=COI&linkSource=FULL_TEXT&linkLocation=Reference make?
- How much income does https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/servlet/linkout?suffix=null&dbid=8&doi=10.1002%2Fart.40323&key=15987481&getFTLinkType=true&doiForPubOfPage=10.1002%2Fart.40323&refDoi=10.1186%2Far1740&linkType=PMID&linkSource=FULL_TEXT&linkLocation=Reference have?
- What's the monthly money flow for https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/servlet/linkout?suffix=null&dbid=128&doi=10.1002%2Fart.40323&key=000231020100017&getFTLinkType=true&doiForPubOfPage=10.1002%2Fart.40323&refDoi=10.1186%2Far1740&linkType=ISI&linkSource=FULL_TEXT&linkLocation=Reference?
- How much revenue does https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/action/getFTRLinkout?url=http%3A%2F%2Fscholar.google.com%2Fscholar_lookup%3Fhl%3Den%26volume%3D7%26publication_year%3D2005%26pages%3DR796-806%26journal%3DArthritis%2BRes%2BTher%26author%3DD%2BAletaha%26author%3DVP%2BNell%26author%3DT%2BStamm%26author%3DM%2BUffmann%26author%3DS%2BPflugbeil%26author%3DK%2BMachold%26title%3DAcute%2Bphase%2Breactants%2Badd%2Blittle%2Bto%2Bcomposite%2Bdisease%2Bactivity%2Bindices%2Bfor%2Brheumatoid%2Barthritis%253A%2Bvalidation%2Bof%2Ba%2Bclinical%2Bactivity%2Bscore&doi=10.1002%2Fart.40323&doiOfLink=10.1186%2Far1740&linkType=gs&linkLocation=Reference&linkSource=FULL_TEXT bring in?
- What is the earnings of https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/servlet/linkout?suffix=null&dbid=32&doi=10.1002%2Fart.40323&key=1%3ACAS%3A528%3ADC%252BD3sXit1yntLs%253D&getFTLinkType=true&doiForPubOfPage=10.1002%2Fart.40323&refDoi=10.1093%2Frheumatology%2Fkeg072&linkType=COI&linkSource=FULL_TEXT&linkLocation=Reference?
- How much money does https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/servlet/linkout?suffix=null&dbid=8&doi=10.1002%2Fart.40323&key=12595618&getFTLinkType=true&doiForPubOfPage=10.1002%2Fart.40323&refDoi=10.1093%2Frheumatology%2Fkeg072&linkType=PMID&linkSource=FULL_TEXT&linkLocation=Reference generate?
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- https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/action/getFTRLinkout?url=http%3A%2F%2Fscholar.google.com%2Fscholar_lookup%3Fhl%3Den%26volume%3D42%26publication_year%3D2003%26pages%3D244-57%26journal%3DRheumatology%2B%2528Oxford%2529%26author%3DJS%2BSmolen%26author%3DFC%2BBreedveld%26author%3DMH%2BSchiff%26author%3DJR%2BKalden%26author%3DP%2BEmery%26author%3DG%2BEberl%26title%3DA%2BSimplified%2BDisease%2BActivity%2BIndex%2Bfor%2Brheumatoid%2Barthritis%2Bfor%2Buse%2Bin%2Bclinical%2Bpractice&doi=10.1002%2Fart.40323&doiOfLink=10.1093%2Frheumatology%2Fkeg072&linkType=gs&linkLocation=Reference&linkSource=FULL_TEXT's financial summary
- Monthly income for https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/action/getFTRLinkout?url=http%3A%2F%2Fscholar.google.com%2Fscholar_lookup%3Fhl%3Den%26volume%3D45%26publication_year%3D2011%26pages%3D481-93%26journal%3DDrug%2BInformation%2BJournal%26author%3DM%2BGe%26author%3DLK%2BDurham%26author%3DRD%2BMeyer%26author%3DW%2BXie%26author%3DN%2BThomas%26title%3DCovariate%25E2%2580%2590adjusted%2Bdifference%2Bin%2Bproportions%2Bfrom%2Bclinical%2Btrials%2Busing%2Blogistic%2Bregression%2Band%2Bweighted%2Brisk%2Bdifferences&doi=10.1002%2Fart.40323&doiOfLink=10.1177%2F009286151104500409&linkType=gs&linkLocation=Reference&linkSource=FULL_TEXT
- See how much https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/servlet/linkout?suffix=null&dbid=32&doi=10.1002%2Fart.40323&key=1%3ASTN%3A280%3ADyaK3s3ktVCmtA%253D%253D&getFTLinkType=true&doiForPubOfPage=10.1002%2Fart.40323&refDoi=e_1_2_8_28_1%3ACOI&linkType=COI&linkSource=FULL_TEXT&linkLocation=Reference makes per month
- How much does https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/servlet/linkout?suffix=null&dbid=8&doi=10.1002%2Fart.40323&key=8478873&getFTLinkType=true&doiForPubOfPage=10.1002%2Fart.40323&refDoi=e_1_2_8_28_1%3APMID&linkType=PMID&linkSource=FULL_TEXT&linkLocation=Reference generate monthly?
- How much income is https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/servlet/linkout?suffix=null&dbid=128&doi=10.1002%2Fart.40323&key=A1993KU05800034&getFTLinkType=true&doiForPubOfPage=10.1002%2Fart.40323&refDoi=e_1_2_8_28_1%3AISI&linkType=ISI&linkSource=FULL_TEXT&linkLocation=Reference earning monthly?
- What's https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/action/getFTRLinkout?url=http%3A%2F%2Fscholar.google.com%2Fscholar_lookup%3Fhl%3Den%26volume%3D20%26publication_year%3D1993%26pages%3D557-60%26journal%3DJ%2BRheumatol%26author%3DGA%2BWells%26author%3DP%2BTugwell%26author%3DGR%2BKraag%26author%3DPR%2BBaker%26author%3DJ%2BGroh%26author%3DDA%2BRedelmeier%26title%3DMinimum%2Bimportant%2Bdifference%2Bbetween%2Bpatients%2Bwith%2Brheumatoid%2Barthritis%253A%2Bthe%2Bpatient%2527s%2Bperspective&doi=10.1002%2Fart.40323&linkType=gs&linkLocation=Reference&linkSource=FULL_TEXT's gross income?
- How much income is https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/servlet/linkout?suffix=null&dbid=32&doi=10.1002%2Fart.40323&key=1%3ACAS%3A528%3ADC%252BD2sXotlSitL4%253D&getFTLinkType=true&doiForPubOfPage=10.1002%2Fart.40323&refDoi=10.1136%2Fard.2006.068304&linkType=COI&linkSource=FULL_TEXT&linkLocation=Reference earning monthly?
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- What's https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/servlet/linkout?suffix=null&dbid=128&doi=10.1002%2Fart.40323&key=000247347900009&getFTLinkType=true&doiForPubOfPage=10.1002%2Fart.40323&refDoi=10.1136%2Fard.2006.068304&linkType=ISI&linkSource=FULL_TEXT&linkLocation=Reference's gross income?
- What's the monthly income of https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/art.40323/action/getFTRLinkout?url=http%3A%2F%2Fscholar.google.com%2Fscholar_lookup%3Fhl%3Den%26volume%3D66%26publication_year%3D2007%26pages%3D893-9%26journal%3DAnn%2BRheum%2BDis%26author%3DDE%2BFurst%26author%3DN%2BGaylis%26author%3DV%2BBray%26author%3DE%2BOlech%26author%3DD%2BYocum%26author%3DJ%2BRitter%26title%3DOpen%25E2%2580%2590label%252C%2Bpilot%2Bprotocol%2Bof%2Bpatients%2Bwith%2Brheumatoid%2Barthritis%2Bwho%2Bswitch%2Bto%2Binfliximab%2Bafter%2Ban%2Bincomplete%2Bresponse%2Bto%2Betanercept%253A%2Bthe%2Bopposite%2Bstudy&doi=10.1002%2Fart.40323&doiOfLink=10.1136%2Fard.2006.068304&linkType=gs&linkLocation=Reference&linkSource=FULL_TEXT?
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