
NCBI . NLM . NIH . GOV {
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Title[redir]:
Cuproptosis: a new form of programmed cell death - PMC
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Keywords {π}
cell, death, dlat, copper, copperinduced, fdx, authors, cells, doi, lipoylation, tsvetkov, pmc, mitochondrial, nlm, proteins, lipoylated, elesclomol, ncbi, search, form, acid, fes, lipoic, protein, programmed, information, science, induces, resulting, stress, cancer, oligomerization, cluster, showed, demonstrated, pubmed, google, scholar, article, intracellular, tca, cycle, including, apoptosis, ferroptosis, excessive, mechanism, dependent, treatment, respiration,
Topics {βοΈ}
genome-wide crisprβcas9 screen lipoic acid-specific antibody copper-induced cell death pmc beta search lipoylated dihydrolipoamide s-acetyltransferase intracellular trace metal publisher site pdf lipoic acid pathway copper-induced death programmed cell death induces cell death lipoic acid modification license information pmcid nat chem biol cell death pathways lipoic acid levels induce cell death cell death differs cell death patterns cell death exist nonapoptotic cell death disulfide bond formation mechanistic information reported excessive accumulation due cell membrane integrity copper-induced form inducing aberrant oligomerization mitochondrial tricarboxylic acid lipoylated dlat leads competing interests united states government reactive oxygen species nondenaturing gel electrophoresis lipoylated dlat protein specific morphological features induce oxidative stress pyruvate dehydrogenase pmc disclaimer significantly reduced compared wild-type mice including mitochondrial shrinkage fdx1 blocked lipoylation wild-type cells cell death excessive copper search log fdx1-knockout cells fdx1-deficient cells dihydrolipoamide dehydrogenase lipoylated proteins
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