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Title[redir]:
Farrerol Induces Cancer Cell Death via ERK Activation in SKOV3 Cells and Attenuates TNF-α-Mediated Lipolysis - PMC
Description:
Farrerol (FA) is a flavanone isolated from the Chinese herbal medicine “Man-shan-hong” (Rhododendron dauricum L.). In the present study, FA decreased the viability of SKOV3 cells in a dose- and time-dependent manner, and it induced G2/M cell cycle ...
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Keywords {🔍}
cells, cell, doi, skov, cancer, treatment, expression, apoptosis, pubmed, google, scholar, figure, cycle, caspase, lipid, cyclin, cachexia, increased, levels, differentiation, farrerol, treated, tnfα, erk, assay, ovarian, data, pmc, wasting, arrest, phase, effects, results, article, decreased, activity, staining, inhibitor, western, cdk, parp, mapk, adipocyte, cleaved, protein, medium, min, measured, effect, significantly,
Topics {✒️}
acetyl-asp-glu-val-asp p-nitroanilide informed consent statement ccaat/enhancer-binding protein α peroxisome proliferator–activated receptor-γ tumor necrosis factor-alpha g0/g1-phase cell-cycle arrest tnf-α-induced adipocyte wasting c-jun n-terminal kinase colorimetric/fluorometric assay kit tnf-α-induced lipid wasting peroxisome proliferator-activated receptor taxol-induced cell death ova-induced allergic asthma induces erk/mapk-mediated apoptosis insulin-stimulated glucose uptake writing—original draft preparation pmc beta search jak2/stat3 signal pathway insulin-induced adipocyte differentiation adipocyte browning-related genes culturing 3t3-l1 preadipocytes extracellular signal-regulated kinase data availability statements impairing tnf-α induction annexin v-fitc active cyclinb1/cdk1 complex crystal violet dye differentiated 3t3-l1 cells differentiated 3t3-l1 adipocytes triglyceride assay kit fa-induced apoptosis occurs supplementary materials included supplementary materials click g0/g1 cells decreased crystal violet solution inhibits cell proliferation g1/g0 phase population real-time pcr control cancer-induced cachexia publisher site pdf fitc-labeled annexin programmed cell death p-erk/erk ratio 3t3-l1 adipocytes treated license information pmcid cell cycle distribution effective early detection estrogen receptor-β protein kinase cdk1/cyclin fa-induced apoptosis induction
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