
NCBI . NLM . NIH . GOV {
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Title[redir]:
NORAD-induced PUMILIO phase separation is required for genome stability - PMC
Description:
Liquid-liquid phase separation (LLPS) has emerged as a major mechanism of subcellular compartmentalization1,2. While the segregation of RNA into phase-separated condensates broadly impacts RNA metabolism3,4, whether and how specific RNAs employ ...
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Keywords {🔍}
pum, norad, cells, cell, rna, fig, data, doi, extended, hct, proteins, phase, droplets, images, number, separation, pres, pubmed, google, scholar, pre, pmc, confocal, concentration, bodies, free, article, fluorescence, circpre, protein, formation, cytoplasmic, shown, xlsx, vitro, line, supplementary, condensates, transcripts, expression, droplet, volume, binding, concentrations, lines, transcript, performed, recruitment, foci, extend,
Topics {✒️}
kfli-digested pav-u6+27-tornado-f30-broccoli plasmid21 pu6-sgrna ef1a-puror-t2a-bfp vector mbp-tev-snap-linker-tev-his6 gov/ij/plugins/track/objects p-body marker dcp2-gfp aforementioned mtth-snap-pum vectors idr-driven pum-pum interactions expressed gfp-tagged wild-type poly-l-lysine coated coverslips purified mbp-snap-pum1hd-wtδidr idr-mediated pum-pum interactions gfp-tagged full-length norad-depleted circpre8-expressing cells 1709047_supp_fig nihms1709047-supplement-1709047_supp_fig 1709047_sd_fig1 nihms1709047-supplement-1709047_sd_fig1 1709047_sd_fig2 nihms1709047-supplement-1709047_sd_fig2 1709047_sd_fig3 nihms1709047-supplement-1709047_sd_fig3 1709047_sd_fig4 nihms1709047-supplement-1709047_sd_fig4 1709047_sd_ed_1 nihms1709047-supplement-1709047_sd_ed_1 1709047_sd_ed_2 nihms1709047-supplement-1709047_sd_ed_2 1709047_sd_ed_3 nihms1709047-supplement-1709047_sd_ed_3 1709047_sd_ed_4 nihms1709047-supplement-1709047_sd_ed_4 1709047_sd_ed_5 nihms1709047-supplement-1709047_sd_ed_5 1709047_sd_ed_6 nihms1709047-supplement-1709047_sd_ed_6 1709047_sd_ed_7 nihms1709047-supplement-1709047_sd_ed_7 1709047_sd_ed_9 nihms1709047-supplement-1709047_sd_ed_9 1709047_sd_ed_10 nihms1709047-supplement-1709047_sd_ed_10 idr-mediated interactions play rna-driven phase separation n-terminal egfp sequence pum-pum interactions independently tailed t-test comparing single-cell sequencing-based technologies primescript rt-pcr mix single-cell transcriptional landscape piggybac xlone-gfp plasmid phase-separated subcellular compartments circpre-expressing cell lines highly multiplex rna-seq sgnorad-infected cell lines rna-induced phase separation pum-mediated accelerated turnover7 pum condensate-inducing circpre4 gfp-tagged pum-wt pmc beta search sgnorad-infected cell line nis-elements ar v5 n-sim analysis software pre-bleach time points p-body marker xrn1
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