
NCBI . NLM . NIH . GOV {
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Title[redir]:
TOX is a critical regulator of tumour-specific T cell differentiation - PMC
Description:
Tumour-specific CD8 T cell dysfunction is a differentiation state that is distinct from the functional effector or memory T cell states1–6. Here we identify the nuclear factor TOX as a crucial regulator of the differentiation of tumour-specific T ...
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Keywords {🔍}
cells, tcrtag, tox, mice, data, expression, fig, cell, wildtype, extended, knockout, scholar, google, doi, infection, isolated, pubmed, red, pmc, tag, naive, liver, shown, article, days, memory, genes, transfer, free, analysis, tumours, gene, flow, tumour, cancer, effector, exhaustion, tcf, human, tils, thy, chronic, stimulation, mouse, experiments, atacseq, control, chromatin, transferred, accessible,
Topics {✒️}
org/packages/release/bioc/html/diffbind 1+pd-1hi/lolaghi/locd39hi/lo tumour-bearing ast×alb-cre mice 50-bp/50-bp paired-end run tumour-bearing ast×alb-cre cd8+cd45ro+pd-1hi tils isolated human tumour-infiltrating pd-1hicd8+ mutant/constitutive active nfat1-overexpressing tag-i-pulsed el4 cells ast×cre-ert2 tumour models sequencing-depth-normalized coverage values tag-peptide-pulsed el4 cells /site/anshulkundaje/projects/blacklists nih-niaid u19 ai11143 nih-niaid r01 ai054977 1531023_supp_tab3 nihms1531023-supplement-1531023_supp_tab3 1531023_supp_tab1 nihms1531023-supplement-1531023_supp_tab1 1531023_supp_tab2 nihms1531023-supplement-1531023_supp_tab2 ctv-labelled naive wild-type albumin-floxstop-sv40 large c57bl/6j wild-type mice nuclear dna-binding factor log2-transformed fold change cd8+cd45ro+cd62l+ central memory ast×cre-ert2 liver tumorigenesis sjl-ptprca pepcb/boyj recipient ast×alb-cre rna-seq-normalized expression values received travel support/honoraria flox-stop cassette leads pmc beta search atac-seq signal intensities ast×cre liver lesions sequencing-depth-normalized coverage ast×alb-cre mice liver-infiltrating wild-type microbe-induced autoreactive cd8+ b16 tumour-bearing mice atac-seq signal profiles cd8+cd45ro+pd-1hi liver tumour-infiltrating tcrtag ast×cre-ert2 mice cd8+cd45ro+pd-1lo activation-induced cell death wild-type versus knockout foundation scholar award cd45ro+pd-1hi pbmcs nfat1 chip–seq samples sequencing protein–dna interactions human cd45ro+pd-1locd39lo
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