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vdr, cells, sox, expression, crc, doi, fig, tumor, cancer, acidic, tissue, google, scholar, stem, pubmed, cell, pmc, microenvironment, data, supplementary, vitamin, article, control, free, cscs, promoter, students, ttest, tissueadherent, stemness, overexpression, found, shown, ppard, results, cultured, significantly, treated, patients, samples, resistance, nuclear, growth, transcription, genes, transcriptional, acidosis, export, binding, phenotype,

Topics {✒️}

sun yat-sen university peroxisome proliferator-activated receptor author contributions jin-fei lin 1 cc tissue-adherent cells tissue-adherent cc cells sequence-specific dna-binding activity hui-yan luo 1 acidic environment-mediated promotion hyperpolarized 13c-labelled bicarbonate pmc beta search license information pmcid real-time quantitative pcr dual-luciferase reporter assay maintaining tumor-initiating cells 150 bp paired-end sequencing polyclonal anti-vdr antibody plv-cmv-vdr-mut energy source driving lactic acid-mediated acidification competing interests stage-iv crc tissues cc tissue adherent high-mobility group domain cc tissue cscs dmem/f12 stem medium polyclonal anti-ppard antibody full-length sox2 promoter small-cell lung cancer advanced crc treated supplementary information [google scholar] 5 nes site-mutant plasmids amplified lineage-survival oncogene cancer stem-cell functions data availability statements data availability statement genome sequence archive metabolic microenvironment reprogramming high/low expression levels important fat-soluble vitamin stage-iv specimens oxaliplatin-resistant hct116 cells cd133-positive crc cells pei-shan hu cells overexpressing vdr patient-derived xenografts normal tissue samples yan-xing chen 1 six2 directly binds

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• Current cancer situation in China: good or bad news from the 2018 Global Cancer Statistics?

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