
NCBI . NLM . NIH . GOV {
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Title[redir]:
Therapeutic potential of targeting MKK3-p38 axis with Capsaicin for Nasopharyngeal Carcinoma - PMC
Description:
Background: Capsaicin is an active compound found in plants of the Capsicum genus; it has a range of therapeutic benefits, including anti-tumor effects. Here we aimed to delineate the inhibitory effects of capsaicin on nasopharyngeal carcinoma ...
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Keywords {🔍}
capsaicin, doi, cell, cells, mkk, npc, pubmed, google, scholar, figure, treatment, cancer, expression, migration, pmc, free, knockdown, effects, article, growth, protein, sune, carcinoma, fuk, apoptosis, tumor, cne, nasopharyngeal, metastasis, pathway, mkkp, assays, progression, found, invasion, performed, patients, assay, data, axis, results, signaling, hone, lines, phosphorylation, anticancer, human, medium, chen, clinical,
Topics {✒️}
inhibiting cyclin-dependent-kinase fetal bovine serum cell counting kit-8 single nucleotide polymorphisms fucose kinase transcription factor downstream epstein-barr virus integration epstein-barr virus propidium iodide staining activating p53 zeb1 protein expression igf1/pi3k/akt pathways pi3k/akt/mtor signaling figure 1a figure 1b pi3k/akt/mtor pathway activated p38 regulates m-mlv rt group e-e-egw modified essential medium p21 dulbecco' dmem cell-cycle inhibitor p27kip1 pi3k-akt axis e-cadherin protein expression egfr-mediated fak/akt dose-dependent capsaicin-induced inhibition activated reverse transcriptase protein data bank ripa lysis buffer reverse transcription tissue microarray nuclease-free water p38 inhibitor treatment p38 inhibitor ly2228820 p38-atf2 axis cyclin d1 dna polymerase taq polymerase serum-free medium specific protein binding qpcr reaction double-edged sword modulating akt/mtor internal reference gapdh zeb1 ha-tagged mkk6 dose-dependent manner
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