
NCBI . NLM . NIH . GOV {
}
Title[redir]:
M6A demethylase ALKBH5 selectively promotes tumorigenesis and cancer stem cell self-renewal in acute myeloid leukemia - PMC
Description:
N6-methyladenosine (m6A), the most abundant internal modification in mRNA, has been implicated in tumorigenesis. As an m6A demethylase, ALKBH5 has been shown to promote the development of breast cancer and brain tumors. However, in acute myeloid ...
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Keywords {π}
alkbh, cells, aml, cell, doi, google, scholar, pubmed, mice, figure, tacc, figures, expression, pmc, article, knockdown, free, mrna, rna, mouse, rrid, analysis, cat, significantly, leukemia, human, data, cancer, targets, normal, wang, control, assays, kit, scientific, stem, ebioscience, huang, zhang, genes, chen, role, thermo, fisher, selfrenewal, shown, transduced, potential, showed, samples,
Topics {βοΈ}
yfp+linβc-kit+scal1βcd34+fcrrii/iii+ org/packages/release/bioc/html/exomepeak ab_469400 anti-mouse ly-6a/ hoxa-pbx3 homeobox-gene signature transforming acidic coiled-coil virally transduced mll-af9-yfp ice-cold phosphate-buffered saline affinity-purified antiβmouse cd16/32 developed full-blown leukemia anti-c-kit-pe-cy7 age-specific mutational interactions endotoxin-free rpmi-1640 supplemented mscv-mll-af9-yfp significantly shortened half-lives alkbh5/m6a/tacc3 axis contributes [google scholar] huang hypoxia-inducible factor 1alpha mouse igg-conjugated protein pmc beta search gr-1βc-kit+ cell population cell growth/proliferation-related pathways single-end 50-base pair ab_465671 mouse/human cd45r anti-mouse ly-6g ab_259529 anti-mouse cd117 io/en/latest/ exomepeak-2 ab_1582236 mouse ly-6g ab_1548788 mouse ly-6g ab_10735092 mouse ly-6g secondary structural switches vitro colony-forming/replating assays wnt/beta-catenin pathway conducted transcriptome-wide rna-seq leukemia stem/initiating cells io/en/stable/index kaplan-meier survival curves organisms/strains nsgs mouse ab_2151827 p21 waf1/cip1 pcl-eco packaging vector metal-ion induced fragmentation hepato-biliary-pancreatic surgery 22 gel-pro analyzer software direct-zol rna miniprep anti-mouse cd117-apc specific anti-m6a antibody leukaemia stem-cell development post-transcriptionally regulating expression ab_627678 anti-alkbh5 antibody n6-methyladenosine rna demethylase n-6-methyladenosine-dependent regulation
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- How much does https://scholar.google.com/scholar_lookup?journal=Proc%20Natl%20Acad%20Sci%20USA&title=Gene%20set%20enrichment%20analysis:%20a%20knowledge-based%20approach%20for%20interpreting%20genome-wide%20expression%20profiles&author=A%20Subramanian&author=P%20Tamayo&author=VK%20Mootha&author=S%20Mukherjee&author=BL%20Ebert&volume=102&publication_year=2005&pages=15545-15550&pmid=16199517&doi=10.1073/pnas.0506580102& pull in monthly?
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