
NCBI . NLM . NIH . GOV {
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Title[redir]:
miR-128 Regulates Tumor Cell CD47 Expression and Promotes Anti-tumor Immunity in Pancreatic Cancer - PMC
Description:
Pancreatic adenocarcinoma (PDAC) is a highly fatal disease worldwide. MicroRNAs (miRNAs) could regulate the protein-coding RNAs related to tumor growth, invasion, and immune evasion. Therefore, the investigation of novel miRNAs may be helpful in the ...
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Keywords {🔍}
cells, pdac, cancer, panc, doi, tumor, pubmed, google, scholar, cell, zeb, overexpression, pmc, expression, macrophages, article, dcs, immune, figure, free, metastasis, antitumor, immunity, mouse, emt, pancreatic, mirnc, results, invasion, phagocytosis, usa, china, mice, figures, control, data, analysis, proliferation, flow, analyzed, study, nkt, tumors, protein, incubated, related, performed, cytometry, growth, showed,
Topics {✒️}
collect pglv3–h1–mir−128–gfp–puro virus anti-cd47-blockade-induced tumor inhibition cd47-signal regulatory protein-α mouse bone-marrow-derived macrophages situ pancreas-tumor-bearing mice incubating peritoneal-cavity-derived macrophages quantitative real-time pcr mir-128 mimic-transfected h7 enhancing anti-tumor immunity pmc beta search analyzing multi-omics data promotes anti-tumor immunity microrna-mediated feedforward loop mir-128-overexpressing panc02 cells peritoneal-cavity-derived macrophages mir-nc overexpression lentiviruses anti-tumor immune response regulatory anti-tumor mechanism emt-inducing transcription factors anti-tumor immune cells epithelial marker e-cadherin cyclic amp-regulated phosphoprotein recombinant mouse m-csf data availability statement zeb/mir-200 feedback loop mir-nc panc02 cells mir-128 lentivirus-infected cells mir-128 mimic-transfected cells humanized anti-cd47 antibody triple-negative breast cancer monoclonal anti-mouse antibodies recombinant mouse gm-csf protein-coding rnas related esophageal squamous-cell cancer cd1d-restricted natural killer enhance anti-tumor immunity mir-nc mimic transfection m-mlv reverse transcriptase anti-mouse f4/80-apc thioglycollate-elicited peritoneal macrophages tumor-bearing mice mouse bone marrow cd47-mediated immune evasion publisher site pdf serum-free medium cd47-sirpα signaling axis anti-cancer therapeutic potential f4/80+gfp+ cells primary tumor sizes bone marrow cells
Questions {❓}
- The ZEB/miR-200 feedback loop–a motor of cellular plasticity in development and cancer?
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