
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Glycoengineering of Natural Killer Cells with CD22 Ligands for Enhanced Anticancer Immunotherapy - PMC
Description:
Adoptive transfer of immune cells is being actively pursued for cancer treatment. Natural killer (NK) cells, a class of cytotoxic immune cells, generally lack inherent selectivities toward cancer. To bestow tumor-targeting abilities and enhance ...
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Keywords {🔍}
cells, cell, figure, pubmed, google, scholar, doi, glycoengineered, free, pmc, cancer, lymphoma, mpbsia, article, glycoengineering, sialic, ligands, engineered, mice, acid, supplementary, surface, binding, metabolic, msnk, raji, patients, natural, enhanced, tumor, antigen, pbs, killer, human, blood, targeting, immunotherapy, abilities, killing, method, polymer, treated, incubation, levels, compared, nlm, cytotoxicities, significant, vivo, ligand,
Topics {✒️}
pe-labeled anti-cd22 mab mpb-sia-α2-6-lac-n33 pmc beta search enhancing n-glycan branching anti-cd20 antibody rituximab patient-derived leukemic samples chimeric antigen receptors chol-p-cd22l1004 trisaccharide neu5acα2-6galβ1-4glcnac b-cell-restricted antigen chimeric antigen receptor sun yat-sen university sialic acid o-acetylation o-acetylated gangliosides expressed atom-transfer radical-polymerization time-lapse imaging video kaplan–meier survival curves cd33-car nk-92 cells nk cell-based immunotherapy cell–cell complex formation free sialic acid b-cell leukemia bestow tumor-targeting abilities raji-luc xenograft model 6-linked sialic acids natural killer cells cd19-targeted car immunotherapy cell-surface sialylated glycans free cd22 protein human cd22-fc incubation wild-type cho cells dmb functionalized bpc-sia pro-inflammatory cytokines cho-hcd22 cells compared enhanced antitumor protection mouse tumor models decrease antigen sensitivity cell receptor signal monosaccharide mpb-sia 1 neuroectoderm derived cells target antigen expression labeled raji cells significantly enhanced cytotoxicities rapidly developing diseases tumor-bearing mice mpb-sia 1 enhanced primary lymphoma cells cd22 binding ligand cd22-dependent manner cd22 ligand expression
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Analytics and Tracking {📊}
- Google Analytics
- Google Analytics 4
- Google Tag Manager
Libraries {📚}
- jQuery
- jQuery module (jquery-3.6.0)
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
- nihcesxway5.hub.nih.gov
Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
- lhcns2.nlm.nih.gov
CDN Services {📦}
- Ncbi