
NCBI . NLM . NIH . GOV {
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Title[redir]:
The potential of retinoids for combination therapy of lung cancer: Updates and future directions - PMC
Description:
Lung cancer is the most common cancer-related death worldwide. Natural compounds have shown high biological and pharmaceutical relevance as anticancer agents. Retinoids are natural derivatives of vitamin A having many regulatory functions in the ...
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Keywords {🔍}
cancer, lung, google, scholar, pubmed, doi, retinoids, cell, acid, cells, retinoic, rarβ, treatment, expression, patients, pmc, article, retinoid, free, growth, combination, phase, survival, bexarotene, vitamin, nsclc, trial, receptor, differentiation, receptors, effect, resistance, tumour, activation, clinical, effects, pathway, human, signaling, inhibition, advanced, res, study, angiogenesis, retinol, metastasis, gene, cisra, stage, protein,
Topics {✒️}
small-cell lung carcinoma membrane signal-free initiation retinoic acid receptor-alpha nci-h460 cell lines retinoic acid receptor–β pmc beta search health grants r01-ca211875 median progression-free survival poor recurrence-free survival small-cell lung cancer small-cell lung cancer retinoid receptor cross-talk cd133+ tumor-initiating cells cutaneous t-cell lymphoma retinoic acid-inducible gene newer retinoid nano-formulations retinoic acid-inducible gprc5a c-myc antisense dna platelet-derived growth factors current drug targets-immune drug-resistant lung cancer holo-retinol-binding protein randomized placebo-controlled trial pi3-akt/erk pathways inhibits tumor-induced angiogenesis pi3k/erk inhibitors represses retinoid receptor-independent activity downregulating c-myc expression 13-cis-retinoic acid modulation enhanced progression-free improves progression-free 9-cis-retinoic acid inhibition egfr/akt/erk pathway ra-bound rarα binds suggested drug-drug interactions ra-induced rarγ degradation surya kant tripathi synthetic mono-aromatic retinoids isoforms including β-carotene ra-sensitive lung cells myc-activated lung cancers multiple angiogenic factors promote anti-proliferative activity retinoic acid receptor trans-retinoic acid trans retinoic acid trans-retinoic acid trans retinoic acid hypoxia-inducible factors egfr/wnt signaling pathways
Questions {❓}
- Averbuch SD, Lung cancer prevention: retinoids and the epidermal growth factor receptor—a phoenix rising?
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- https://doi.org/10.1074/jbc.274.53.38225's total income per month
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- How profitable is https://scholar.google.com/scholar_lookup?journal=EMBO%20J&title=Phosphorylation%20by%20p38MAPK%20and%20recruitment%20of%20SUG-1%20are%20required%20for%20RA-induced%20RAR%CE%B3%20degradation%20and%20transactivation&author=M%20Gianni&author=A%20Bauer&author=E%20Garattini&author=P%20Chambon&author=C%20Rochette-Egly&volume=21&issue=14&publication_year=2002&pages=3760-3769&pmid=12110588&doi=10.1093/emboj/cdf374&?
- https://doi.org/10.1210/mend.9.7.7476969's financial summary
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- Earnings of https://doi.org/10.1042/BJ20051794
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- How much does https://scholar.google.com/scholar_lookup?journal=J.%20Biol.%20Chem&title=Molecular%20cloning%20and%20characterization%20of%20a%20novel%20retinoic%20acid-inducible%20gene%20that%20encodes%20a%20putative%20G%20protein-coupled%20receptor&author=Y%20Cheng&author=R%20Lotan&volume=273&issue=52&publication_year=1998&pages=35008-35015&pmid=9857033&doi=10.1074/jbc.273.52.35008& earn?
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- Get to know what's the income of https://doi.org/10.3390/ijms140715029
- How much revenue does https://scholar.google.com/scholar_lookup?journal=Int.%20J.%20Mol.%20Sci&title=DNA%20methylation%20and%20cancer%20diagnosis&author=Y%20Delpu&author=P%20Cordelier&author=W%20Cho&author=J%20Torrisani&volume=14&issue=7&publication_year=2013&pages=15029-15058&pmid=23873296&doi=10.3390/ijms140715029& produce monthly?
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- How much money does https://scholar.google.com/scholar_lookup?title=And%20medicine,%20Retinoids%20and%20Human%20Cancer,%20the%20Retinoids:%20Biology&author=W%20Hong&publication_year=1994& generate?
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- Profit of https://scholar.google.com/scholar_lookup?title=Retinoids%20and%20Cancer%20in%20Experimental%20Animals%20in%20The%20Retinoids:%20Biology,%20Chemistry,%20and%20Medicine&author=R%20Moon&author=R%20Metha&author=K%20Rao&author=MB%20Sporn&author=AB%20Roberts&publication_year=1994&
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- How much income does https://scholar.google.com/scholar_lookup?journal=J.%20Natl.%20Cancer%20Inst&title=Randomized%20phase%20III%20intergroup%20trial%20of%20isotretinoin%20to%20prevent%20second%20primary%20tumors%20in%20stage%20I%20non-small-cell%20lung%20cancer&author=SM%20Lippman&author=JJ%20Lee&author=DD%20Karp&author=EE%20Vokes&author=SE%20Benner&volume=93&issue=8&publication_year=2001&pages=605-618&pmid=11309437&doi=10.1093/jnci/93.8.605& have?
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- What's the financial gain of https://scholar.google.com/scholar_lookup?journal=N.%20Engl.%20J.%20Med&title=The%20effect%20of%20vitamin%20E%20and%20beta%20carotene%20on%20the%20incidence%20of%20lung%20cancer%20and%20other%20cancers%20in%20male%20smokers&volume=330&issue=15&publication_year=1994&pages=1029-1035&pmid=8127329&doi=10.1056/NEJM199404143301501&?
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- Revenue of https://scholar.google.com/scholar_lookup?journal=N.%20Engl.%20J.%20Med&title=Lack%20of%20effect%20of%20long-term%20supplementation%20with%20beta%20carotene%20on%20the%20incidence%20of%20malignant%20neoplasms%20and%20cardiovascular%20disease&author=CH%20Hennekens&author=JE%20Buring&author=JE%20Manson&author=M%20Stampfer&author=B%20Rosner&volume=334&issue=18&publication_year=1996&pages=1145-1149&pmid=8602179&doi=10.1056/NEJM199605023341801&
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- What's the profit of https://doi.org/10.1007/BF00180817?
- What's the profit of https://scholar.google.com/scholar_lookup?journal=Invest.%20New%20Drugs&title=A%20phase%20II%20trial%20of%20a%20differentiating%20agent%20(tRA)%20with%20cisplatin-VP%2016%20chemotherapy%20in%20advanced%20non-small%20cell%20lung%20cancer&author=R%20Thiruvengadam&author=JO%20Atiba&author=SH%20Azawi&volume=14&issue=4&publication_year=1996&pages=395-401&pmid=9157076&doi=10.1007/BF00180817&?
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- Financial intake of https://doi.org/10.1200/JCO.1997.15.2.790
- Get to know https://scholar.google.com/scholar_lookup?journal=J.%20Clin.%20Oncol&title=Initial%20clinical%20trial%20of%20a%20selective%20retinoid%20X%20receptor%20ligand,%20LGD1069&author=VA%20Miller&author=FM%20Benedetti&author=JR%20Rigas&author=AL%20Verret&author=DG%20Pfister&volume=15&issue=2&publication_year=1997&pages=790-795&pmid=9053506&doi=10.1200/JCO.1997.15.2.790&'s earnings
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- How much does https://scholar.google.com/scholar_lookup?journal=J.%20Clin.%20Oncol&title=Multi-institutional%20phase%20I/II%20trial%20of%20oral%20bexarotene%20in%20combination%20with%20cisplatin%20and%20vinorelbine%20in%20previously%20untreated%20patients%20with%20advanced%20non-small-cell%20lung%20cancer&author=FR%20Khuri&author=JR%20Rigas&author=RA%20Figlin&author=RJ%20Gralla&author=DM%20Shin&volume=19&issue=10&publication_year=2001&pages=2626-2637&pmid=11352954&doi=10.1200/JCO.2001.19.10.2626& make?
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