
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Inhibiting EMT, stemness and cell cycle involved in baicalin-induced growth inhibition and apoptosis in colorectal cancer cells - PMC
Description:
Although baicalin, a flavonoid derived from Scutellaria baicalensis Georgi, has been reported to have anti-tumor activity in various cancers, the molecular mechanism remains imperfect. Here, we show that baicalin inhibits cell growth, migration and ...
Matching Content Categories {📚}
- Science
- Education
- Health & Fitness
Content Management System {📝}
What CMS is ncbi.nlm.nih.gov built with?
Custom-built
No common CMS systems were detected on Ncbi.nlm.nih.gov, and no known web development framework was identified.
Traffic Estimate {📈}
What is the average monthly size of ncbi.nlm.nih.gov audience?
🚀🌠 Tremendous Traffic: 10M - 20M visitors per month
Based on our best estimate, this website will receive around 10,538,143 visitors per month in the current month.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Ncbi.nlm.nih.gov Make Money? {💸}
We're unsure if the website is profiting.
The purpose of some websites isn't monetary gain; they're meant to inform, educate, or foster collaboration. Everyone has unique reasons for building websites. This could be an example. Ncbi.nlm.nih.gov might be plotting its profit, but the way they're doing it isn't detectable yet.
Keywords {🔍}
cells, baicalin, cell, crc, doi, cancer, hct, assay, treatment, fig, levels, mice, tumor, treated, growth, protein, pubmed, google, scholar, rko, apoptosis, stemness, colorectal, group, emt, data, control, vivo, metastasis, cycle, spheres, inhibition, showed, concentrations, inhibited, proteins, stem, days, effect, tumors, results, pmc, μgml, medium, photographed, concentration, migration, invasion, formation, positive,
Topics {✒️}
dimethyl sulfoxide cell counting kit-8 protease inhibitor cocktail tgfβ-induced epithelial-mesenchymal transition suppressing tgf-β/smad pathway mapk pathway 26 exogenous tgf-β1-induced emt inhibiting tgfβ/smad pathway activated frequently 2% triton x-100 peroxidase/dab inhibiting tgfβ/smads pathway decreased exogenous tgfβ1-induced targeting tgfβ1/smad pathway ripa lysis buffer envision detection kit bio-rad gel imager tgf-β/smads pathway exogenous tgfβ1-induced emt flavonoid derived pmc beta search bleomycin-induced pulmonary fibrosis tgfβ1-induced cell migration [pubmed] [google scholar] inhibiting cell cycle/emt/stemness baicalin-induced growth inhibition promote epithelial-mesenchymal transition cell cycle-related proteins nf-κb-p65 pmc copyright notice 5ml dmso diluted increasing apoptosis-related proteins washing/blocking buffer wound-healing assay showed sphere-cultured hct116 cells cell cycle arrest induce cell arrest publisher site pdf low/high dose baicalin low-/high-dose baicalin western-blot data showed regulating apoptosis-related proteins cck-8 assays showed cell signaling technology serum-free medium serum-free mccoy' induces cell apoptosis hct116-gfp xenograft mice suppressing cell cycle negative/positive control reagents
Social Networks {👍}(6)
External Links {🔗}(78)
- https://doi.org/10.7150/jca.37242's revenue stream
- How much does https://creativecommons.org/licenses/by/4.0/ earn?
- Learn how profitable http://ivyspring.com/terms is on a monthly basis
- How profitable is https://doi.org/10.1002/ijc.25516?
- Learn how profitable https://scholar.google.com/scholar_lookup?journal=Int%20J%20Cancer&title=Estimates%20of%20worldwide%20burden%20of%20cancer%20in%202008:%20GLOBOCAN%202008&author=J%20Ferlay&author=HR%20Shin&author=F%20Bray&author=D%20Forman&author=C%20Mathers&volume=127&publication_year=2010&pages=2893-917&pmid=21351269&doi=10.1002/ijc.25516& is on a monthly basis
- How much income is https://doi.org/10.3322/caac.21262 earning monthly?
- https://scholar.google.com/scholar_lookup?journal=CA%20Cancer%20J%20Clin&title=Global%20cancer%20statistics,%202012&author=LA%20Torre&author=F%20Bray&author=RL%20Siegel&author=J%20Ferlay&author=J%20Lortet-Tieulent&volume=65&publication_year=2015&pages=87-108&pmid=25651787&doi=10.3322/caac.21262&'s total income per month
- How much does https://doi.org/10.1007/s13304-016-0359-y gross monthly?
- How much does https://scholar.google.com/scholar_lookup?journal=Updates%20Surg&title=Worldwide%20burden%20of%20colorectal%20cancer:%20a%20review&author=P%20Favoriti&author=G%20Carbone&author=M%20Greco&author=F%20Pirozzi&author=RE%20Pirozzi&volume=68&publication_year=2016&pages=7-11&pmid=27067591&doi=10.1007/s13304-016-0359-y& generate monthly?
- https://doi.org/10.1038/ncpgasthep0473's financial summary
- How much income does https://scholar.google.com/scholar_lookup?journal=Nat%20Clin%20Pract%20Gastroenterol%20Hepatol&title=Mechanisms%20of%20disease:%20from%20stem%20cells%20to%20colorectal%20cancer&author=SA%20McDonald&author=SL%20Preston&author=MJ%20Lovell&author=NA%20Wright&author=JA%20Jankowski&volume=3&issue=5&publication_year=2006&pages=267-74&pmid=16673006&doi=10.1038/ncpgasthep0473& have?
- See how much https://doi.org/10.1007/s12094-009-0397-8 makes per month
- Revenue of https://scholar.google.com/scholar_lookup?journal=Clin%20Transl%20Oncol&title=Adjuvant%20chemotherapy%20for%20stages%20II,%20III%20and%20IV%20of%20colon%20cancer&author=C%20Gr%C3%A1valos&author=I%20Garc%C3%ADa-Escobar&author=P%20Garc%C3%ADa-Alfonso&author=J%20Cassinello&author=D%20Mal%C3%B3n&volume=11&issue=8&publication_year=2009&pages=526-33&pmid=19661027&doi=10.1007/s12094-009-0397-8&
- What's the monthly money flow for https://doi.org/10.3816/CCC.2002.n.004?
- How much does https://scholar.google.com/scholar_lookup?journal=Clin%20Colorectal%20Cancer&title=Adjuvant%20therapy%20of%20colon%20cancer:%20a%20review&author=TJ%20Hobday&author=C%20Erlichman&volume=1&issue=4&publication_year=2002&pages=230-6&pmid=12450421&doi=10.3816/CCC.2002.n.004& net monthly?
- How much does https://doi.org/10.1002/cncr.24760 gross monthly?
- Learn about the earnings of https://scholar.google.com/scholar_lookup?journal=Cancer&title=Annual%20report%20to%20the%20nation%20on%20the%20status%20of%20cancer,%201975-2006,%20featuring%20colorectal%20cancer%20trends%20and%20impact%20of%20interventions%20(risk%20factors,%20screening,%20and%20treatment)%20to%20reduce%20future%20rates&author=BK%20Edwards&author=E%20Ward&author=BA%20Kohler&author=C%20Eheman&author=AG%20Zauber&volume=116&publication_year=2010&pages=544-73&pmid=19998273&doi=10.1002/cncr.24760&
- What are the total earnings of https://doi.org/10.1016/j.cell.2009.11.007?
- How much does https://scholar.google.com/scholar_lookup?journal=Cell&title=Epithelial-mesenchymal%20transitions%20in%20development%20and%20disease&author=JP%20Thiery&author=H%20Acloque&author=RY%20Huang&author=MA%20Nieto&volume=139&issue=5&publication_year=2009&pages=871-90&pmid=19945376&doi=10.1016/j.cell.2009.11.007& net monthly?
- What is the monthly revenue of https://doi.org/10.1007/s10555-008-9169-0?
- What's the monthly money flow for https://scholar.google.com/scholar_lookup?journal=Cancer%20Metastasis%20Rev&title=EMT,%20the%20cytoskeleton,%20and%20cancer%20cell%20invasion&author=M%20Yilmaz&author=G%20Christofori&volume=28&issue=1-2&publication_year=2009&pages=15-33&pmid=19169796&doi=10.1007/s10555-008-9169-0&?
- Get to know https://doi.org/10.1186/2001-1326-3-23's earnings
- How much does https://scholar.google.com/scholar_lookup?journal=Clin%20Transl%20Med&title=Biomechanics%20of%20TGF%CE%B2-induced%20epithelial-mesenchymal%20transition:%20implications%20for%20fibrosis%20and%20cancer&author=JW%20O'Connor&author=EW%20Gomez&volume=3&publication_year=2014&pages=23&pmid=25097726&doi=10.1186/2001-1326-3-23& pull in?
- What are the earnings of https://doi.org/10.1016/j.mod.2003.06.005?
- See how much https://scholar.google.com/scholar_lookup?journal=Mech%20Dev&title=Mechanisms,%20mechanics%20and%20function%20of%20epithelial-mesenchymal%20transitions%20in%20early%20development&author=D%20Shook&author=R%20Keller&volume=120&issue=11&publication_year=2003&pages=1351-83&pmid=14623443&doi=10.1016/j.mod.2003.06.005& makes per month
- How much does https://doi.org/10.1038/nrm3758 pull in monthly?
- Monthly income for https://scholar.google.com/scholar_lookup?journal=Nat%20Rev%20Mol%20Cell%20Biol&title=Molecular%20mechanisms%20of%20epithelial-mesenchymal%20transition&author=S%20Lamouille&author=J%20Xu&author=R%20Derynck&volume=15&issue=3&publication_year=2014&pages=178-96&pmid=24556840&doi=10.1038/nrm3758&
- Earnings of https://doi.org/10.1016/j.yexcr.2018.07.022
- What is the monthly revenue of https://scholar.google.com/scholar_lookup?journal=Exp%20Cell%20Res&title=An%20extracellular%20matrix%20(ECM)%20model%20at%20high%20malignant%20colorectal%20tumor%20increases%20chondroitin%20sulfate%20chains%20to%20promote%20epithelial-mesenchymal%20transition%20and%20chemoresistance%20acquisition&author=T%20Hoshiba&volume=370&issue=2&publication_year=2018&pages=571-8&pmid=30016638&doi=10.1016/j.yexcr.2018.07.022&?
- How much does https://doi.org/10.1016/j.clcc.2018.05.007 bring in each month?
- What is the earnings of https://scholar.google.com/scholar_lookup?journal=Clin%20Colorectal%20Cancer&title=Cancer%20Stemness,%20Immune%20Cells,%20and%20Epithelial-Mesenchymal%20Transition%20Cooperatively%20Predict%20Prognosis%20in%20Colorectal%20Carcinoma&author=F%20Xu&author=S%20Li&author=J%20Zhang&author=L%20Wang&author=X%20Wu&volume=17&issue=3&publication_year=2018&pages=e579-e592&pmid=29921496&doi=10.1016/j.clcc.2018.05.007&?
- Financial intake of https://doi.org/10.1002/jcb.25196
- Revenue of https://scholar.google.com/scholar_lookup?journal=J%20Cell%20Biochem&title=Notch-1%20promotes%20stemness%20and%20epithelial%20to%20mesenchymal%20transition%20in%20colorectal%20cancer&author=AW%20Fender&author=JM%20Nutter&author=TL%20Fitzgerald&author=FE%20Bertrand&author=G%20Sigounas&volume=116&issue=11&publication_year=2015&pages=2517-27&pmid=25914224&doi=10.1002/jcb.25196&
- Learn how profitable https://doi.org/10.1111/jcmm.13725 is on a monthly basis
- Get to know what's the income of https://scholar.google.com/scholar_lookup?journal=J%20Cell%20Mol%20Med&title=Astragaloside%20IV%20modulates%20TGF-%CE%B21-dependent%20epithelial-mesenchymal%20transition%20in%20bleomycin-induced%20pulmonary%20fibrosis&author=W%20Qian&author=X%20Cai&author=Q%20Qian&author=W%20Zhang&author=D%20Wang&volume=22&issue=9&publication_year=2018&pages=4354-65&pmid=29971947&doi=10.1111/jcmm.13725&
- What is the monthly revenue of https://doi.org/10.1006/phrs.2000.0761?
- What's the monthly money flow for https://scholar.google.com/scholar_lookup?journal=Pharmacol%20Res&title=Protective%20effects%20of%20flavonoids%20in%20the%20roots%20of%20Scutellaria%20baicalensis%20Georgi%20against%20hydrogen%20peroxide-induced%20oxidative%20stress%20in%20HS-SY5Y%20cells&author=Z%20Gao&author=K%20Huang&author=H%20Xu&volume=43&issue=2&publication_year=2001&pages=173-8&pmid=11243719&doi=10.1006/phrs.2000.0761&?
- Check the income stats for https://doi.org/10.1016/j.ctrv.2008.09.005
- https://scholar.google.com/scholar_lookup?journal=Cancer%20Treat%20Rev&title=New%20therapeutic%20aspects%20of%20flavones:%20the%20anticancer%20properties%20of%20Scutellaria%20and%20its%20main%20active%20constituents%20Wogonin,%20Baicalein%20and%20Baicalin&author=M%20Li-Weber&volume=35&issue=1&publication_year=2009&pages=57-68&pmid=19004559&doi=10.1016/j.ctrv.2008.09.005&'s revenue stream
- How much profit is https://doi.org/10.3390/molecules17043844 making per month?
- Financial intake of https://scholar.google.com/scholar_lookup?journal=Molecules&title=Baicalin%20induces%20apoptosis%20in%20SW620%20human%20colorectal%20carcinoma%20cells%20in%20vitro%20and%20suppresses%20tumor%20growth%20in%20vivo&author=WC%20Chen&author=TH%20Kuo&author=YS%20Tzeng&author=YC%20Tsai&volume=17&issue=4&publication_year=2012&pages=3844-57&pmid=22456615&doi=10.3390/molecules17043844&
- What's the financial intake of https://doi.org/10.1038/srep17407?
- How much profit does https://scholar.google.com/scholar_lookup?journal=Sci%20Rep&title=Therapeutic%20effect%20of%20baicalin%20on%20experimental%20autoimmune%20encephalomyelitis%20is%20mediated%20by%20SOCS3%20regulatory%20pathway&author=Y%20Zhang&author=X%20Li&author=B%20Ciric&author=CG%20Ma&author=B%20Gran&volume=5&publication_year=2015&pages=17407&pmid=26616302&doi=10.1038/srep17407& make?
- What's the income generated by https://doi.org/10.1016/j.phrs.2006.11.007 each month?
- https://scholar.google.com/scholar_lookup?journal=Pharmacol%20Res&title=Baicalin%20attenuates%20oxygen-glucose%20deprivation-induced%20injury%20via%20inhibiting%20NMDA%20receptor-mediated%205-lipoxygenase%20activation%20in%20rat%20cortical%20neurons&author=QF%20Ge&author=X%20Hu&author=ZQ%20Ma&author=JR%20Liu&author=WP%20Zhang&volume=55&issue=2&publication_year=2007&pages=148-57&pmid=17187986&doi=10.1016/j.phrs.2006.11.007& income
- What's the total monthly financial gain of https://doi.org/10.1038/aps.2009.196?
- How much does https://scholar.google.com/scholar_lookup?journal=Acta%20Pharmacol%20Sin&title=Baicalin%20attenuates%20oxygen-glucose%20deprivation-induced%20injury%20by%20inhibiting%20oxidative%20stress-mediated%205-lipoxygenase%20activation%20in%20PC12%20cells&author=CT%20Li&author=WP%20Zhang&author=SH%20Fang&author=YB%20Lu&author=LH%20Zhang&volume=31&issue=2&publication_year=2010&pages=137-44&pmid=20139896&doi=10.1038/aps.2009.196& earn?
- Profit of https://doi.org/10.1007/s11064-009-9953-4
- What's the income generated by https://scholar.google.com/scholar_lookup?journal=Neurochem%20Res&title=Neuroprotective%20effect%20of%20baicalin%20in%20a%20rat%20model%20of%20permanent%20focal%20cerebral%20ischemia&author=XK%20Tu&author=WZ%20Yang&author=SS%20Shi&author=CH%20Wang&author=CM%20Chen&volume=34&issue=9&publication_year=2009&pages=1626-34&pmid=19294503&doi=10.1007/s11064-009-9953-4& each month?
- Learn how profitable https://scholar.google.com/scholar_lookup?journal=Iran%20J%20Pharm%20Res&title=Effects%20and%20mechanism%20of%20baicalin%20on%20apoptosis%20of%20cervical%20cancer%20HeLa%20cells%20in-vitro&author=Y%20Peng&author=ZZ%20Fu&author=CS%20Guo&author=YX%20Zhang&author=Y%20Di&volume=14&issue=1&publication_year=2015&pages=251-61&pmid=25561931& is on a monthly basis
- How much does https://doi.org/10.1142/S0192415X06003801 pull in monthly?
- See how much https://scholar.google.com/scholar_lookup?journal=Am%20J%20Chin%20Med&title=Baicalin-induced%20apoptosis%20is%20mediated%20by%20Bcl-2-dependent,%20but%20not%20p53-dependent,%20pathway%20in%20human%20leukemia%20cell%20lines&author=DE%20Shieh&author=HY%20Cheng&author=MH%20Yen&author=LC%20Chiang&author=CC%20Lin&volume=34&issue=2&publication_year=2006&pages=245-61&pmid=16552836&doi=10.1142/S0192415X06003801& makes per month
- Profit of https://scholar.google.com/scholar_lookup?journal=Int%20J%20Clin%20Exp%20Med&title=Baicalin%20inhibits%20PDGF-induced%20proliferation%20and%20migration%20of%20airway%20smooth%20muscle%20cells&author=G%20Yang&author=JQ%20Li&author=JP%20Bo&author=B%20Wang&author=XR%20Tian&volume=8&issue=11&publication_year=2015&pages=20532-9&pmid=26884970&
- How profitable is https://doi.org/10.1177/1010428317729933?
- Get to know what's the income of https://scholar.google.com/scholar_lookup?journal=Tumour%20Biol&title=Cancer%20stem%20cells%20and%20differentiation%20therapy&author=X%20Jin&author=X%20Jin&author=H%20Kim&volume=39&issue=10&publication_year=2017&pages=1010428317729933&pmid=29072131&doi=10.1177/1010428317729933&
- How much does https://doi.org/10.1016/j.yexcr.2017.10.018 rake in every month?
- Earnings of https://scholar.google.com/scholar_lookup?journal=Exp%20Cell%20Res&title=Diagnostic%20and%20Prognostic%20Biomarkers%20in%20Ovarian%20Cancer%20and%20the%20Potential%20Roles%20of%20Cancer%20Stem%20Cells-%20an%20updated%20review&author=T%20Muinao&author=HP%20Deka%20Boruah&author=M%20Pal&volume=362&issue=1&publication_year=2018&pages=1-10&pmid=29079264&doi=10.1016/j.yexcr.2017.10.018&
- How much does https://doi.org/10.1159/000084505 earn?
- Find out how much https://scholar.google.com/scholar_lookup?journal=Cells%20Tissues%20Organs&title=Transforming%20growth%20factor-beta%20signaling%20during%20epithelial-mesenchymal%20transformation:%20implications%20for%20embryogenesis%20and%20tumor%20metastasis&author=A%20Nawshad&author=D%20Lagamba&author=A%20Polad&author=ED%20Hay&volume=179&publication_year=2005&pages=11-23&pmid=15942189&doi=10.1159/000084505& earns monthly
- How much profit is https://doi.org/10.1016/j.molmed.2008.03.004 making per month?
- https://scholar.google.com/scholar_lookup?journal=Trends%20Mol%20Med&title=Epithelial-mesenchymal%20transition%20and%20the%20invasive%20potential%20of%20tumors&author=N%20Gavert&author=A%20Ben-Ze'ev&volume=14&publication_year=2008&pages=199-209&pmid=18406208&doi=10.1016/j.molmed.2008.03.004&'s financial summary
- What's the total monthly financial gain of https://doi.org/10.1038/362849a0?
- Get to know https://scholar.google.com/scholar_lookup?journal=Nature&title=Thymocyte%20apoptosis%20induced%20by%20p53-dependent%20and%20independent%20pathways&author=AR%20Clarke&author=CA%20Purdie&author=DJ%20Harrison&author=RG%20Morris&author=CC%20Bird&volume=362&issue=6423&publication_year=1993&pages=849-52&pmid=8479523&doi=10.1038/362849a0&'s earnings
- Revenue of https://doi.org/10.4161/cc.21997
- Earnings of https://scholar.google.com/scholar_lookup?journal=Cell%20Cycle&title=Putting%20the%20brakes%20on%20p53-driven%20apoptosis&author=K%20H%C3%B6pker&author=H%20Hagmann&author=S%20Khurshid&author=S%20Chen&author=B%20Schermer&volume=11&issue=22&publication_year=2012&pages=4122-8&pmid=22983126&doi=10.4161/cc.21997&
- https://scholar.google.com/scholar_lookup?journal=Cancer%20Res&title=Dual%20antitumor%20effects%20of%205-fluorouracil%20on%20the%20cell%20cycle%20in%20colorectal%20carcinoma%20cells:%20a%20novel%20target%20mechanism%20concept%20for%20pharmacokinetic%20modulating%20chemotherapy&author=R%20Yoshikawa&author=M%20Kusunoki&author=H%20Yanagi&author=M%20Noda&author=JI%20Furuyama&volume=61&issue=3&publication_year=2001&pages=1029-37&pmid=11221829&'s total income per month
- Discover the revenue of https://github.com/ncbi
- How much revenue does https://www.google.com/maps/place/8600+Rockville+Pike,+Bethesda,+MD+20894/%4038.9959508, -77.101021,17z/data%3D!3m1!4b1!4m5!3m4!1s0x89b7c95e25765ddb%3A0x19156f88b27635b8!8m2!3d38.9959508! 4d-77.0988323 bring in?
- How much does https://www.nlm.nih.gov/web_policies.html pull in?
- What's the total monthly financial gain of https://www.nih.gov/institutes-nih/nih-office-director/office-communications-public-liaison/freedom-information-act-office?
- How much revenue does https://www.hhs.gov/vulnerability-disclosure-policy/index.html produce monthly?
- Learn how profitable https://support.nlm.nih.gov/?pagename=cloudpmc-viewer%3Apmc%3Aarticle%3Ajournal is on a monthly basis
- Find out how much https://www.nlm.nih.gov/accessibility.html earns monthly
- How much income is https://www.nlm.nih.gov/careers/careers.html earning monthly?
- What's the total monthly financial gain of https://www.nlm.nih.gov/?
- What's the total monthly financial gain of https://www.nih.gov/?
- Profit of https://www.hhs.gov/
- Learn about the earnings of https://www.usa.gov/
Analytics and Tracking {📊}
- Google Analytics
- Google Analytics 4
- Google Tag Manager
Libraries {📚}
- jQuery
- jQuery module (jquery-3.6.0)
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
- nihcesxway5.hub.nih.gov
Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
- lhcns2.nlm.nih.gov
CDN Services {📦}
- Ncbi