NCBI . NLM . NIH . GOV {
}
We began analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC7026425/, but it redirected us to https://pmc.ncbi.nlm.nih.gov/articles/PMC7026425/. The analysis below is for the second page.
Title[redir]:
Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients - PMC
Description:
Current treatments for clear cell renal cell cancer (ccRCC) are insufficient because two-thirds of patients with metastases progress within two years. Here we report the identification and characterization of a cancer stem cell (CSC) population in ...
Title[redir]:
Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients - PMC
Description:
Current treatments for clear cell renal cell cancer (ccRCC) are insufficient because two-thirds of patients with metastases progress within two years. Here we report the identification and characterization of a cancer stem cell (CSC) population in ...
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- Science
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Custom-built
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What is the average monthly size of ncbi.nlm.nih.gov audience?
🚀🌠 Tremendous Traffic: 10M - 20M visitors per month
Based on our best estimate, this website will receive around 10,538,143 visitors per month in the current month.
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Keywords {🔍}
cells, doi, fig, cell, supplementary, notch, wnt, pubmed, google, scholar, cultures, cancer, tumors, ccrcc, patients, organoids, stem, sphere, data, expression, cxcrmetcd, pmc, article, genes, tumor, renal, free, spheres, signaling, performed, icg, organoid, pdx, dapt, cscs, treatment, gene, inhibitors, carcinoma, kidney, singlecell, days, shown, inhibition, analysis, bars, primary, growth, effects, sequencing,
Topics {✒️}
β-catenin-lef1 fusion protein39 altered wnt1/beta-catenin expression beta-catenin/tcf4 interaction blocks von hippel lindau fac-sorted cxcr4+met+cd44+ cells activating wnt/beta-catenin pathway author contributions cxcr4+met+cd44+ cells amounted cxcr4+met+cd44+ cells share fac-sorted cxcr4+met+cd44+ cxcr4+met+cd44+ cells correlated single cxcr4+met+cd44+ cells cxcr4+met+cd44+ cells revealed tcf/beta-catenin transcription pmc beta search advanced renal-cell carcinoma β-catenin-lef1-transfected spheres cultured cxcr4+met+cd44+ cells modified htseq-count script cg-prkdcscid il2rgtm1wjl/szj 1 µg β-catenin-lef1 cxcr4+met+cd44+ cells obtained single-cell rna-seq ordinately regulates cxcr4/cxcl12 β-catenin inhibitor lf350 competing interests visualizing high-dimensional data vhl stabilizes β-catenin mann–whitney-u-test cxcr4+met+cd44+ profile alexa-conjugated secondary antibodies anti-cd45 micro-beads single-cell rna amplification 20 ng prl-tk plasmid small-cell lung cancer cxcr4−met−cd44− cells cxcr4+met+cd44+ cells cxcr4−met−cd44−cells wnt−driven mammary cancer gamma-secretase/presenilin inhibitors anti-rabbit-pacific blue sided mann–whitney test distal-tubule marker calbindin test tumor-initiating capacity genome-wide expression profiling cancer-initiating cells isolated stem cell-specific genes ubiquitylating beta-catenin human kidney-derived cells = 125 cxcr4+met+cd44+ spheres
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