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Keywords {🔍}

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Topics {✒️}

gold-standard s-ldsc+ldak method s-ldsc+ldak enrichment estimates 1038/s41588-019-0464-1 reconciling s-ldsc s-ldsc+ldak produced org/alkesgroup/ldscore/1000g_phase3_baselineld_v1 s-ldsc enrichment estimates flexibly combines baseline-ld running s-ldsc+ldak pmc beta search s-ldsc+ldak method �gold-standard” method produced higher likelihoods �baseline-ld+ldak” model baseline-ld+ldak model baseline-ld+ldak models attained lower likelihoods �gazal-ld model” comprising linkage disequilibrium-dependent architecture supplementary materials included epigenetic fine mapping produced unstable estimates low-frequency variants8 functional enrichment estimates ldak enrichment estimates lower enrichment estimates publisher site pdf s-ldsc method s-ldsc+ldak baseline-ld model4 s-ldsc method4 genome-wide snps sumher enrichment estimates nih k99 hg010160-01 nih dp5-od024582 org/alkesgroup/ukbb/ uk biobank resource uk biobank traits minor allele frequency obtained similar conclusions supplementary tables 1–10 ld-dependent architectures imputed hrc snps baseline-ld model genetic variance estimation s-ldsc estimand estimate functional enrichment analyzed genotypes imputed ldak model assigns fine-mapped snps united states government

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