
NCBI . NLM . NIH . GOV {
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Title[redir]:
IL-33 Signaling Alters Regulatory T Cell Diversity in Support of Tumor Development - PMC
Description:
Regulatory T cells (Tregs) can impair anti-tumor immune responses and are associated with poor prognosis in multiple cancer types. Tregs in human tumors span diverse transcriptional states distinct from those of peripheral Tregs, but their ...
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Keywords {🔍}
tregs, cells, genes, cell, tumor, expression, lung, treg, scholar, google, doi, pubmed, pmc, mice, article, free, figure, gene, cancer, programs, program, development, rrid, data, analysis, tumors, expressed, kpfstfl, regulatory, mouse, model, signature, performed, human, time, test, tconv, ilrl, figures, diversity, cxcr, signaling, tconvs, function, methods, minutes, thermo, scrnaseq, msln, fisher,
Topics {✒️}
hrp-polymer-conjugated secondary antibodies endo-free maxiprep kits org/web/packages/lme4/index org/web/packages/jade/index high-dimensional single-cell analysis t-bet+cxcr3+ treg population large-scale single-cell data [google scholar] saito droplet-based scrna-seq references akama-garren eh [google scholar] bankhead [google scholar] bettelli full-length scrna-seq 1 confirming treg-specific recombination pmc beta search single-cell rna-seq scrna-seq data reported treg-depleted animals succumb klrg1 2f1 pe-cy7 limit infection-induced pathology plate-based scrna-seq rat anti-mouse cd8alpha rabbit anti-mouse prosp treg-specific st2 deficiency anti-cd45-pe-cf594 rabbit anti-prosurfactant protein oncogene-driven lung adenocarcinoma stromal foxp3/cd3 ratio single-cell rna sequencing plex-fd kit bulk rna-seq treg-specific ablation 5ml collagenase/dnase buffer identifying foxp3-expressing suppressor treg-specific il1rl1 deletion rank-based input format t-bet+cxcr3+ regulatory pro-inflammatory treg phenotype bd perm/wash buffer gene-set enrichment visualization promote anti-tumor immunity pro-tumorigenic treg subsets depleting tumor-specific tregs high-quality cells noted low-expression gene filtering enhance anti-tumor immunity flpo-gfp-os intratracheally 2-sample mann-whitney-wilcoxon tissue-specific programs included suppress th1 responses
Questions {❓}
- Experimental mouse tumour models: what can be learnt about human cancer immunology?
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