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Title[redir]:
Ziziphus spina-christi Leaf Extract Suppressed Mercury Chloride-Induced Nephrotoxicity via Nrf2-Antioxidant Pathway Activation and Inhibition of Inflammatory and Apoptotic Signaling - PMC
Description:
Exposure to heavy metals, including mercury chloride (HgCl2), is associated with severe health problems. This study was designed to investigate HgCl2-induced nephrotoxicity and evaluate the protective role of Ziziphus spina-christi leaf extract ...
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Keywords {🔍}
doi, kidney, zscle, renal, google, scholar, mercury, expression, pubmed, tissue, rats, spinachristi, antioxidant, hgcl, ziziphus, extract, oxidative, figure, animals, exposure, glutathione, control, data, pmc, compared, change, leaf, induced, effect, function, hgcltreated, response, ilβ, tnfα, treatment, mrna, article, protective, intoxication, effects, stress, activities, levels, results, injury, expressed, significance, nephrotoxicity, pathway, heavy,
Topics {✒️}
nrf2/nf-κb/p53 signaling pathway sirt1/nrf2/tnf-α signaling pathway spina-christi leaf extract ziziphus spina-christi fruits cadmium-induced cortical damage gong-niu-huang wan realgar-induced oxidative stress mpp+-induced oxidative stress quantitative real-time pcr real-time quantitative pcr tumor necrosis factor-α average biological half-life nikon eclipse e200-led qrt-pcr data revealed nrf2-antioxidant response pathway pmc beta search ziziphus spina-christi platinum-lined graphite furnace investigate hgcl2-induced nephrotoxicity qrt-pcr results revealed hg-induced oxidative injury hgcl2-induced oxidative stress hgcl2-induced oxidative damage cadmium-induced hepatotoxicity hg-induced oxidative stress hgcl2-induced renal injury hgcl2-intoxicated rats accompanied nrf2-antioxidant pathway activation mercury-induced hepatorenal toxicity antioxidant signaling pathway real-time pcr nf-κb pathways publisher site pdf manganese-dependent superoxide dismutase spina-christi leaves mercury-induced renal toxicity producing liver injury hg-induced renal toxicity kidney injury molecule-1 activated nuclear factor 6-gingerol alleviate liver glutathione-dependent antioxidant enzymes oxidative stress induced license information pmcid apoptotic signaling rafa oxidative stress biomarkers zscle-treated rats revealed 4 mg/kg hgcl2 dissolved extensive evidences demonstrate pcr cycling conditions
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