
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Honokiol inhibits breast cancer cell metastasis by blocking EMT through modulation of Snail/Slug protein translation - PMC
Description:
Honokiol (HNK), an active compound isolated from traditional Chinese medicine Magnolia officinalis, has shown potent anticancer activities. In the present study, we investigated the effects of HNK on breast cancer metastasis in vitro and in vivo, as ...
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Keywords {🔍}
cells, hnk, doi, cancer, snail, breast, cell, slug, pubmed, google, scholar, expression, pmc, protein, article, free, emt, metastasis, fig, inhibits, mrna, levels, migration, honokiol, mcf, mdamb, translation, results, treatment, decreased, wang, invasion, ecadherin, assay, treated, shown, epithelial, tumor, analysis, control, group, transition, usa, china, lung, compared, vitro, showed, mouse, metastatic,
Topics {✒️}
suppress wnt/β-catenin signaling dsrna-dependent interferon-beta production transcription 3/zeb1/e-cadherin axis wnt/ beta-catenin signaling mapk1/slug/vimentin feedback loop specific pathogen-free conditions suppressing ezh2/mir-143 axis zinc-finger transcription factors microrna-34a dependent manner tumor-stromal cross-talk pmc beta search epithelial marker e-cadherin snail/e-cadherin pathway hnk-induced er stress repressing e-cadherin expression shanghai ziyi-reagent company competing interests reverse transcription-quantitative pcr primary anti-snail antibody e-cadherin gene expression mda-mb-231 cell lines increased e-cadherin expression downregulating e-cadherin expression hnk-treated cell lines e-cadherin expression levels upregulated e-cadherin expression transcription factors snail/slug e-cadherin expression level hnk-treated side population acta pharmacol sin quantitative rt-pcr tumor-bearing mice tgf-beta promotes publisher site pdf ecl detection system cell line resource cell signaling technology serum-free medium 4t1 cell lines key transcription factors snail/slug mrna expression cancer cell survival potent anticancer drug pi3k/pten pathway transcription factor snail promoting tumor invasion epithelial-mesenchymal transition breast cancer cell cell-cell adhesion e-cadherin levels
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