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Keywords {🔍}

doi, maltol, liver, apap, google, scholar, pubmed, injury, apoptosis, apapinduced, oxidative, protein, hepatotoxicity, mice, stress, group, nfκb, pmc, wang, signaling, figure, effect, caspase, pathway, results, expression, levels, staining, acute, free, article, effects, kinase, bcl, normal, pikakt, protective, hepatic, inflammatory, gsh, pretreatment, study, acetaminophen, cype, food, bax, tissues, analysis, inflammation, tnfα,

Topics {✒️}

s-adenosyl-l-methionine protection nrf2/ho-1-mediated oxidative stress alcohol-induced hepatic injury anti-apap-induced-hepatotoxicity effect ampk/pi3k/akt signaling pathways s-adenosyl-l-methionine apap-induced hepatic injury contributed reagents/materials/analysis tools pro-inflammatory cytokine tnf-α alcohol-induced oxidative damage nf-kappab-mediated fas overexpression apap-induced liver injury drug-induced liver injury apap-induced oxidative stress nrf2-mediated liver protection caspase-mediated anti-apoptotic effect reactive oxygen/nitrogen species acetaminophen-induced acute hepatotoxicity tgf-beta1-mediated activation exerts anti-tumor efficacy ampk/akt/gsk3β pathway n-acetyl-p-aminophenol oxidative stress-mediated activation acetaminophen-induced liver damage failed pcna-related hemostasis pmc beta search enhances trail-induced apoptosis nf-κb signal pathways pro-apoptotic signaling pathway acetaminophen-induced mitochondrial dysfunction h22 tumor-bearing mice oxidative stress-mediated inflammation pi3k/akt signaling pathways dose-dependent drug hepatotoxicity ikk/nf-kappab signaling tris-buffered saline-tween phosphatidylinositol 3-kinase/protein kinase pi3k/akt signaling pathway maltol-mediated beneficial effect inhibit nf-κb activation nf-κb signal activation nf-kappab-dependent mechanism nf-κb signaling pathway maltol anti-apap hepatotoxicity akt/mtor-mediated inhibition free nf-κb [39] mediated liver injury acute liver injury hepatic oxidative stress apap-induced hepatotoxicity

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