
NCBI . NLM . NIH . GOV {
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Title[redir]:
Enhancing humoral immunity via sustained-release implantable microneedle patch vaccination - PMC
Description:
Vaccine kinetics, the timing of antigen and/or adjuvant delivery to lymphoid organs, have recently been shown to substantially influence immune responses to subunit vaccines, but strategies to control vaccine kinetics in a clinically translatable ...
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Keywords {🔍}
trimer, silk, release, vaccine, doi, pubmed, google, scholar, mns, fig, antigen, pmc, article, skin, bolus, cells, free, responses, delivery, hiv, sustained, antibody, immunization, mice, patches, igg, adjuvant, antibodies, appendix, application, sosip, humoral, immunity, fibroin, time, serum, trimers, kinetics, adjuvants, lns, day, shown, vaccines, control, injections, tips, envelope, studies, plates, pgt,
Topics {✒️}
b220−cd4+cd44+cxcr5+pd1+ tfh anti-cd21/cd35 bv421 antibody activation-induced marker assay org/lookup/suppl/doi trimer-specific antibody-secreting cells pain-free vaccine administration needle-free platform amenable b220+ igdlow pna+gl7+ needle-free platform translatable rabbit anti-goat igg solid micron-sized projections rabbit anti-6xhis antibody antigen-specific germinal center continuous-delivery osmotic pumps optilab t-rex instruments structure-specific monoclonal antibodies class-switched antibody titers pmc beta search long-lived plasma cells rapid diffusion-regulated release trimer-specific tfh cells serum-neutralizing antibody titers trimer-specific igg ascs water-insoluble silk films antigen-specific plasma cells patch-delivered antigen combined ln-localized antigen colocalized quaternary-dependent antibodies targeting sustained-release implantable mns antibody-based hiv vaccine 3disco-tissue clearing method lower igg titers critical swelling/degradation threshold solid pyramidal microneedle dermal dendritic cells increased germinal center β-sheet crystallinity trimer-specific igg strong translational relevance supplementary materials included patch-released adjuvant elicited methanol-annealed silk mns murine antibody responses trimer-specific tfh vaccine-loaded silk tips follicular dendritic cell serum igg responses assessed mucosal igg enhanced immune responses therapeutic monoclonal antibodies
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- jQuery
- jQuery module (jquery-3.6.0)
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
- nihcesxway5.hub.nih.gov
Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
- lhcns2.nlm.nih.gov
CDN Services {📦}
- Ncbi