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Title[redir]:
m6A methyltransferase METTL3 suppresses colorectal cancer proliferation and migration through p38/ERK pathways - PMC
Description:
Purpose: Although many biological processes are involved in the modification of N6-methyladenosine (m6A), the exact role of m6A in the development of malignant tumors remains unclear. Methyltransferase 3 (METTL3) is a major RNA N6-methyladenosine ...
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Keywords {๐}
mettl, crc, doi, expression, cancer, cell, proliferation, cells, migration, knockdown, pubmed, google, scholar, pmc, invasion, figure, methyltransferase, perk, survival, overexpression, tumor, article, progression, patients, free, role, rna, analysis, metastasis, hct, colorectal, pathways, assay, erk, inhibitors, signaling, cellular, development, usa, open, tab, inhibited, nlm, study, results, significantly, clinical, mins, group, carcinogenesis,
Topics {โ๏ธ}
aff4/nf-ฮบb/myc signaling network aff4/nf-kappab/myc signaling network plagl2/igf2/beta-catenin signal pathways org/web/packages/maxstat/index conjugated anti-rabbit igg poor disease-free survival pmc beta search modifying p53-mediated signaling14 ythdf2-dependent posttranscriptional silencing dna-methylation-mediated silencing pearson chi-square test mek-erk signalling pathway p38/erk signaling pathway rna n6-methyladenosine methyltransferase rna n6-methyladenosine methyltransferase real-time proliferation publisher site pdf mapk signaling pathway mammalian rna demethylase kaplanโmeier method anti-mettl3 antibody cell signaling technology methods crc specimens mettl3 promotes proliferation rna remains unclear license information pmcid rpmi-1640 culture medium promoted liver carcinogenesis nuclear rna impacts rna metabolism publ rna soc dna methylation plays renal cancer cell crc cell proliferation secondary horseradish peroxidase cell death dis mettl3 promoted losses longer survival time sybr green kit cancer cell survival crc remain poor crc disease progression plko control vectors united states government future therapeutic advances written informed consent 5 ฮผg/ml polybrene oli oligo sequence leica fluorescence microscope roche applied sciences
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