
NCBI . NLM . NIH . GOV {
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Title[redir]:
Antitumor Effects of Berberine on Gliomas via Inactivation of Caspase-1-Mediated IL-1β and IL-18 Release - PMC
Description:
Gliomas arise in the glial cells of the brain or spine and are the most prevalent and devastating type of brain tumors. Studies of tumor immunology have established the importance of the tumor micro-environment as a driver of oncogenesis. ...
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Keywords {🔍}
berberine, cells, ilβ, cell, caspase, glioma, gliomas, significantly, doi, expression, cancer, protein, pubmed, google, scholar, brain, treatment, signaling, pmc, figures, analysis, levels, tissues, tumor, emt, article, study, activation, acyyadcmk, mrna, increased, migration, free, effects, found, erk, human, treated, compared, effect, usa, assay, wound, performed, results, figure, normal, decreased, survival, collected,
Topics {✒️}
nuclear factor-[kappa] enzyme-linked immunosorbent assay il-1β-mediated nf-κb leads erk/mapk signaling fitc-conjugated anti-rabbit igg molecular brain neoplasia ac-yyad-cmk significantly attenuated ac-yyad-cmk significantly resulted erk/mapk recombinant il-1r antagonist ac-yyad-cmk significantly increased regulated gene activation anti-α-sma antibodies berberine-induced anti-tumor activity cancer genome atlas epithelial-mesenchymal transition dimethyl sulfoxide polyvinylidene difluoride � standard error il-1β-mediated intracellular signaling nf-κb pathway ac-yyad-cmk treatment nf-κb activation nf-κb signaling pro-interleukin il-1β pmc beta search activated form 100 μm ac-yyad-cmk disease-free rate specific anti-proliferation effect nuclear translocation real-time pcr kaplan-meier survival curve unpaired student t-test carcinogenesis-related gene expression ac-yyad-cmk mesenchymal transition markers tumorous brain tissues nf-κb targeting cancer-related inflammation il-1beta induced angiogenesis publisher site pdf wnt/β-catenin pathway regulated neoplasia specific intrinsic pathways human glioblastoma cells studied molecular alterations written informed consent mmp-2
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