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Keywords {🔍}

google, scholar, doi, rna, pubmed, pmc, mrna, article, free, cell, fto, mettl, cells, ythdf, methylation, translation, wang, mam, zhang, proteins, liu, demethylation, protein, readers, binding, nmethyladenosine, regulation, cap, writer, cellular, expression, transcripts, chen, shi, complex, nuclear, localization, mol, functions, wei, stability, nature, sites, recent, modification, figure, reader, human, modifications, gene,

Topics {✒️}

mrna-binding factor rbm15/spenito a-dependent translation control [google scholar] fu histone h3 trimethylation high-throughput sequencing approaches [google scholar] cui n-terminal low-complexity sequence pmc beta search generating mettl3-mettl14-wtap complex favor rna-binding events sex-specific splicing factor zinc finger ccch-type facilitates hippocampus-dependent learning human hnrnp a2/b1 6ma-modified ssdna revealed transcriptome-wide distribution pattern uhplc-qqq-ms/ms highly-sensitive mass spectrometry uv-induced damage sites n6-methyladenosine binding protein rna n6-methyladenosine methyltransferase affect starvation-induced autophagy modulates rna-protein interactions microrna-mediated mrna degradation ythdf2-dcas13b delivery resulted stimulation-dependent regulation exemplified multi-component writer complex stem-loop structured rna s-adenosylmethionine homeostasis factor bind u-riched regions deciphering ptm-mediated regulation cap-specific methyltransferase pcif1 single-cell rna-seq long-term memory relies high-throughput sequencing machinery component wtap/fl m6a-modified rna probe mettl16-mediated mat2a methylation cap-binding proteins inside divergent cell-type-specific m6a-mediated regulation pathways breast cancer cells mettl3-eif3h enhances translation injury-induced axon regeneration ythdf1-dcas13b enhanced translation cellular-localization dependent functions n6methyladenosine-dependent regulation 3t3-l1 cell differentiation cap-m6am-modified mrna transcript-specific m6a methylation

Questions {❓}

• Functions of Readers: Redundant or Convoluted?
• How are the selectivity, both transcript selectivity and site selectivity, achieved?
• How are these readers recognizing their target transcripts?
• What is the molecular basis for differential cellular localization of FTO?
• Why does context matter in m6A epitranscriptomics?

Social Networks {👍}(6)

• https://twitter.com/ncbi
• https://www.facebook.com/ncbi.nlm
• https://www.linkedin.com/company/ncbinlm
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• https://www.facebook.com/nationallibraryofmedicine
• https://www.youtube.com/user/NLMNIH

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• https://doi.org/10.1016/j.cell.2012.05.003's financial summary
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