
NCBI . NLM . NIH . GOV {
}
Title[redir]:
The Retinoid X Receptor Agonist, 9-cis UAB30, Inhibits Cutaneous T-cell Lymphoma Proliferation Through the SKP2-p27kip1 Axis - PMC
Description:
Bexarotene (Targretinยฎ) is currently the only FDA approved retinoid X receptor (RXR) -selective agonist for the treatment of cutaneous T-cell lymphomas (CTCLs). The main side effects of bexarotene are hypothyroidism and elevation of serum ...
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Keywords {๐}
cells, cell, uab, bexarotene, skp, pkip, rexinoids, protein, google, scholar, hut, myla, pubmed, doi, ctcl, treatment, mrna, fig, treated, cycle, control, proteasome, cancer, pmc, lines, activity, apoptosis, psma, article, values, dmso, annexin, data, free, degradation, early, decrease, proliferation, lower, stability, stained, increase, checkpoint, population, expression, average, acid, percent, suppressed, effective,
Topics {โ๏ธ}
text nihms1002625-supplement-text cutaneous t-cell lymphoma cutaneous t-cell lymphomas continuous t-cell strains lxr/rxr-activated transcripts cyclin-dependent kinase inhibitor methylnitrosourea-induced mammary cancers n-myc-dependent decrease blue x-ray films cell cycle-related markers s2 nihms1002625-supplement-s2 increased tg/lipid biosynthesis n-myc-independent decrease neuroblastoma sh-sy5y differentiation skp2 mrna/ฮฒ-actin mrna family f-box proteins pmc beta search commonly prescribed long-term enhanced proteasome-dependent degradation table 1 nihms1002625-supplement-table_1 klf4-mediated tumor initiation identifying low-toxicity drugs pmc copyright notice trans retinoic acid cell cycle g0/g1 f-box proteins skp2 consistent time-dependent increase ฮฒ-actin mrna relative cell line-dependent f-box protein skp2 cell apoptosis induced steady-state psma7 mrna t-cell disorders 20s proteasome activity publisher site pdf s-phase kinase percent cell population supplementary materials included paired t-tests 20s catalytic subunit 13-cis retinoic acid 9-cis retinoic acid 20s proteolytic activity g2/g1 ratio analysis flow cytometry assay primary tumor suppressor time-dependent manner low-toxicity 9-cis uab30 suppressing cell proliferation license information pmcid
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- What's the financial outcome of https://doi.org/10.1016/s0092-8674(00)81239-8?
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- How much income does https://scholar.google.com/scholar_lookup?journal=Cell&title=Mice%20lacking%20p21CIP1/WAF1%20undergo%20normal%20development,%20but%20are%20defective%20in%20G1%20checkpoint%20control&author=C%20Deng&author=P%20Zhang&author=JW%20Harper&author=SJ%20Elledge&author=P%20Leder&volume=82&issue=4&publication_year=1995&pages=675-84&pmid=7664346&doi=10.1016/0092-8674(95)90039-x& have?
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- What's https://scholar.google.com/scholar_lookup?journal=Carcinogenesis&title=Suppression%20of%20human%20pancreatic%20cancer%20cell%20proliferation%20by%20AGN194204,%20an%20RXR-selective%20retinoid&author=S%20Balasubramanian&author=RA%20Chandraratna&author=RL%20Eckert&volume=25&issue=8&publication_year=2004&pages=1377-85&pmid=14976133&doi=10.1093/carcin/bgh122&'s gross income?
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