
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Intratumoral CD56bright natural killer cells are associated with improved survival in bladder cancer - PMC
Description:
Natural killer (NK) cells are effective at killing tumors in a non-MHC restricted manner and are emerging targets for cancer therapy but their importance in bladder cancer (BC) is poorly defined. NK cells are commonly subdivided into populations ...
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Keywords {🔍}
cells, doi, cell, bladder, intratumoral, cdbright, cddim, pubmed, google, scholar, lymphocytes, tumor, cancer, mhc, figure, pmc, cytotoxicity, survival, tumors, human, article, natural, killer, expression, subsets, patients, stage, free, clone, compared, surface, flow, immune, target, populations, function, including, higher, functional, data, immunol, analysis, cytokine, pathologic, nkgd, improved, production, increased, subset, nlm,
Topics {✒️}
carboxyfluorescein succinimidyl ester fixable viability dye cd45+cd14-cd19-cd3-ilt3-ckit grambsch-therneau residual-based test fluorescence-activated cell sorting cd45+cd11b+cd68-cd14+ cells cd45+cd11b+cd68-cd14- cells natural-killer group 2 cfse-labeled target cells chain related protein ul16-binding proteins p-values represent log-rank tailed unpaired t-tests pmc beta search cd45+cd11b+cd68+ cells apc-antigen presenting cells activated cd56dim/bright cells cd163-cd45+cd11b+cd68+ cd163+cd45+cd11b+cd68+ live cd45+cd3+cells cancer-specific mortality variable tnf-α cytokine production tailed unpaired t-test cd45+cd11b+cd33+ cells cd56bright natural killer natural killer cells cd56-defined nk cells supplementary materials oncotarget-09-36492-s001 muscle-invasive urothelial carcinoma stress-inducible mica tumor-infiltrating lymphocytes compared increased cytokine production proportional hazards assumptions cd3- ckit- cells cd8 tumor-infiltrating lymphocytes advanced bladder cancer cancer-specific survival cancer specific survival higher cytokine production low cytokine production nk cell phenotypes including cytokine production nk cell subsets dc- dendritic cells nk cell cytotoxicity cancer-specific mortality advanced ovarian cancer human bladder tumor supplementary materials figures rt4 target cells
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