
NCBI . NLM . NIH . GOV {
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Title[redir]:
miR-153 inhibits the migration and the tube formation of endothelial cells by blocking the paracrine of angiopoietin 1 in breast cancer cells - PMC
Description:
The sprouting of endothelial cells is the first step of tumor angiogenesis. Our previous study suggests that miR-153 suppresses breast tumor angiogenesis partially through targeting hypoxia-induced factor (HIF1α). In this study, we demonstrated that ...
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Keywords {🔍}
ang, cells, doi, cancer, mcf, breast, migration, angiogenesis, tumor, cell, pubmed, google, scholar, expression, huvecs, endothelial, primary, tube, formation, proliferation, angiopoietin, levels, conditioned, growth, tissues, fig, medium, pmc, media, assay, test, mrna, protein, shown, lines, images, sprouting, study, suppresses, ectopic, results, liu, inhibited, mimics, inhibits, article, secretion, activity, blood, sirnas,
Topics {✒️}
pcdh-cmv-mcs-ef1-puro-3 × flag-3 × ha lentiviral vector brca1/ctip/zbrk1 repressor complex pkcζ/β-catenin/rac1 pathways secondary anti-rabbit igg targeting hypoxia-induced factor anti-mouse igg antibodies pkcζ/β-catenin complex lncrnas hif1a-as2 facilitates clinical breast cancer samples ethical standards disclosure adenoviral-delivered angiopoietin-1 reduces pmc beta search mitogen-activated protein kinase dual-luciferase reporter assays coated µ-slide angiogenesis mda-mb-231 cell lines secreted ~ 70-kda glycoprotein belonging pcdh-ang1 expression plasmid pmir-ang1-3′utr-mut1 pmir-ang1-3′utr-mut3 serum-free medium methods cell lines ang1/tie2 pathways play pre-existing blood vessels pmir-ang1-3′utr-wt angiopoietin-1/tie-2 activation contributes breast cancer cell breast cancer tissue pmir-report™ system pathologic vascular growth pcdh lentivirus system breast cancer tissues publisher site pdf hcc1937 cell lines real-time pcr suppress tumor growth license information pmcid abi-7900ht system breast cancer cells breast cancer angiogenesis ire1alpha-xbp1 pathway negative correlative trend human ethics committee promotes tumor growth egm-2 bullet kit protease inhibitor cocktail endothelial cell sprouting adjacent normal tissues exogenous ang1 protein matched adjacent tissues
Questions {❓}
- How is blood vessel growth regulated in normal and neoplastic tissue?
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