
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Lupus antibodies induce behavioral changes mediated by microglia and blocked by ACE inhibitors - PMC
Description:
Nestor et al. examine how lupus antibodies that enter the brain cause neuronal dysfunction and cognitive impairment. The results show that activated microglia are critical for neuronal damage and that inhibiting them can preserve neuronal function ...
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Keywords {π}
dnrab, mice, google, scholar, doi, pubmed, microglia, neurons, hmgb, ace, dendritic, neuronal, pmc, fig, article, free, brain, microglial, studies, min, cognitive, antibody, activation, group, test, place, lps, hippocampus, plx, sections, inhibitors, cells, captopril, model, loss, lupus, cell, impairment, complexity, kowal, stevens, receptor, disease, number, compared, study, angiotensin, staining, significant, alzheimers,
Topics {βοΈ}
n-methyl-d-aspartate receptor 50 Β΅g/ml poly-d-lysine high-mobility group box-1 pmc beta search angiotensin-converting enzyme inhibitors goat anti-rabbit antibody nmdarβhmgb1βc1q complex forms biotinylated anti-rabbit antibody 16-channel multi-electrode array angiotensin-converting enzyme polymorphisms [google scholar] ohrui pilocarpine-induced status epilepticus place field size pmc copyright notice place field sizes brain-penetrating ace inhibitors enlarged place fields nr2 glutamate receptor renin-angiotensin system blockade kolmogorov-smirnov nonparametric statistics angiotensin-converting enzyme angiotensin converting enzyme centrally acting inhibitors fluorescent-conjugated secondary antibody endogenous danger signaling dnrab-mediated neuronal death microglia-dependent synapse loss pro-inflammatory cytokine release receptor 4-dependent signaling enhances nmdar signaling supplementary materials included captopril exhibited significantly place fields behaved blue-labeled cell bodies promotes brain recovery standard chow-treated mice impaired spatial memory postischemic rat brain dnrab+ plx5622-treated compared dnrab-mediated neuronal damage captopril-treated dnrab+ mice c1q-dependent dendritic loss representative place fields saline-treated dnrab+ animals saline-treated dnrab+ mice fd neuro technologies cell-specific deletion preserved dendritic complexity ace inhibitor treatment super-resolution microscopy
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- https://scholar.google.com/scholar_lookup?journal=J.%20Neurochem.&title=Neuroprotective%20role%20of%20bradykinin%20because%20of%20the%20attenuation%20of%20pro-inflammatory%20cytokine%20release%20from%20activated%20microglia&author=M.%20Noda&author=Y.%20Kariura&author=U.%20Pannasch&author=K.%20Nishikawa&author=L.%20Wang&volume=101&publication_year=2007&pages=397-410&pmid=17402969&doi=10.1111/j.1471-4159.2006.04339.x&'s financial summary
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- Learn about the earnings of https://doi.org/10.1111/jgs.12415
- How much cash flow does https://scholar.google.com/scholar_lookup?journal=J.%20Am.%20Geriatr.%20Soc.&title=Angiotensin-converting%20enzyme%20inhibitors%20and%20Alzheimer%E2%80%99s%20disease%20progression%20in%20older%20adults:%20results%20from%20the%20R%C3%A9seau%20sur%20la%20Maladie%20d%E2%80%99Alzheimer%20Fran%C3%A7ais%20cohort&author=M.E.%20Soto&author=G.A.%20van%20Kan&author=F.%20Nourhashemi&author=S.%20Gillette-Guyonnet&author=M.%20Cesari&volume=61&publication_year=2013&pages=1482-1488&pmid=24000874&doi=10.1111/jgs.12415& have monthly?
- How much does https://doi.org/10.1146/annurev-neuro-061010-113810 bring in each month?
- What are the earnings of https://scholar.google.com/scholar_lookup?journal=Annu.%20Rev.%20Neurosci.&title=The%20complement%20system:%20an%20unexpected%20role%20in%20synaptic%20pruning%20during%20development%20and%20disease&author=A.H.%20Stephan&author=B.A.%20Barres&author=B.%20Stevens&volume=35&publication_year=2012&pages=369-389&pmid=22715882&doi=10.1146/annurev-neuro-061010-113810&?
- How much does https://doi.org/10.1016/j.cell.2007.10.036 pull in?
- How much does https://scholar.google.com/scholar_lookup?journal=Cell.&title=The%20classical%20complement%20cascade%20mediates%20CNS%20synapse%20elimination&author=B.%20Stevens&author=N.J.%20Allen&author=L.E.%20Vazquez&author=G.R.%20Howell&author=K.S.%20Christopherson&volume=131&publication_year=2007&pages=1164-1178&pmid=18083105&doi=10.1016/j.cell.2007.10.036& generate monthly?
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- Explore the financials of https://doi.org/10.1084/jem.20111986
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- https://www.nlm.nih.gov/web_policies.html's total income per month
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