
NCBI . NLM . NIH . GOV {
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Title[redir]:
Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium - PMC
Description:
Ferroptosis is a death program executed via selective oxidation of arachidonic acid–phosphatidylethanolamines (AA-PE) by 15-lipoxygenases. In mammalian cells and tissues, ferroptosis has been pathogenically associated with brain, kidney, and liver ...
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Keywords {🔍}
doi, cells, aeruginosa, ploxa, figure, google, scholar, cell, pubmed, hbe, death, ferroptosis, pmc, free, article, δwspf, supplemental, lox, pseudomonas, protein, minutes, hours, analysis, supernatants, performed, supernatant, incubated, data, patients, loxatn, panel, isolates, biofilm, aape, mammalian, clinical, activity, bacterial, samples, sequence, hooaape, bacteria, mutant, ferroptotic, ferrostatin, proferroptotic, control, scientific, lipid, gpx,
Topics {✒️}
pro-ferroptotic signal 15-hoo-sa/aa-pe 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine pro-ferroptotic 15-hoo-aa-pe products 15-hoo-aa-pe–sensitized hbe cells produce 15-hoo-aa-pe acting long-chain pufa-coa pro-ferroptotic 15-hoo-aa-pe ploxa-generated 15-hoo-aa-pe act 15-hoo-aa-pe–sensitized cells global priority list nta-ni affinity chromatography ploxa substrate stearoyl-arachidonoyl-pe de la fuente-núñez epoxide-mediated differential packaging p53-mediated ferroptotic responses diode-pumped light engine supplementary materials included lower respiratory tract pmc beta search yielding 15-hoo-aa-pes pro-ferroptotic hydroxy-pls aeruginosa–induced synchronized death exogenous 15-hoo-aa-pe directly reduce hydroperoxy-pls 15-hoo-aa-pe dominate fatty acid–free bsa nutrient-deprived cancer cells extensively drug-resistant strains puc18-minitn7t-gm-gw compromise immune-stimulating functions predictive pro-ferroptotic biomarkers nta-ni affinity column s-lens rf level generating pro-ferroptotic signals results biofilm-producing prokaryote pmc copyright notice chronic biofilm-based infections pro-ferroptotic oxidation substrate high-performance energy minimization 15-hoo-aa-pe signals reverse-phase lc-ms acyl-coa synthesis pro-ferroptotic lpo products membrane-damaging lipid peroxidation oxidize host aa-pe house-generated analysis workflow generated 15-hoo-aa-pe z-vad-fmk regulating host-pathogen interactions ms/ms-based identification
Questions {❓}
- Bacterial lipoxygenases, a new subfamily of enzymes?
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