
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Targeting T Cell Metabolism for Improvement of Cancer Immunotherapy - PMC
Description:
There has been significant progress in utilizing our immune system against cancer, mainly by checkpoint blockade and T cell-mediated therapies. The field of cancer immunotherapy is growing rapidly but durable clinical benefits occur only in a small ...
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Keywords {🔍}
cells, cell, google, scholar, pubmed, doi, cancer, pmc, metabolic, article, free, metabolism, function, differentiation, immune, glycolysis, signaling, tme, acid, activation, glucose, tumor, effector, fatty, antitumor, immunol, reprogramming, amino, growth, glutamine, expression, role, acids, key, immunity, macrophages, generation, therapeutic, kinase, mtor, pathways, protein, memory, mdscs, energy, immunotherapy, promote, factor, coinhibitory, receptors,
Topics {✒️}
granulocyte-macrophage colony-stimulating factor granulocyte colony-stimulating factor forkhead-box p3 cd11b+cd14+human leukocyte antigen-antigen mitogen-activated protein kinase nitric oxide b7-cd28 ligand-receptor family flavin adenine dinucleotide 6-phosphofructo-2-kinase/fructose-2 programmed death-ligand 1 oxidase assembly protein interferon-γ pyruvate dehydrogenase kinase hypoxia-inducible factor 1α forkhead-box amp-activated protein kinase alternatively activated macrophage mtorc2-irf4 signaling axis overcome interferon-mediated cytotoxicity pyruvate dehydrogenase kinases cyclin-dependent kinase-1 gm-csf cd11b+ly6g+ly6clow cell-surface markers fumarate hydratase loss acetyl-coa carboxylase 1 mct-mediated function 5-aminoimidazole-4-carboxamide ribonucleotide endoplasmic reticulum hypoxia-inducible factor-1alpha pentose phosphate pathway ifn-γ fumarate hydratase chimeric antigen receptor-expressing activation-induced t-cell death ifn-β-mediated cytotoxic signals succinate dehydrogenase hypoxia-inducible factor-1 slc7a5–slc3a2 antiporter hypoxia-induced hif-1α oncogene-activated pi3k pathway nuclear factor mechanistic/mammalian target myc proto-oncogene chimeric antigen receptor inducible t-cell costimulator glucose transporter glut1 tnf receptor superfamily ldha lag-3 branched-chain amino acids
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- What's the income generated by https://doi.org/10.1016/j.celrep.2017.07.075 each month?
- What's the income of https://scholar.google.com/scholar_lookup?journal=Cell%20Rep&title=PDL1%20signals%20through%20conserved%20sequence%20motifs%20to%20overcome%20interferon-mediated%20cytotoxicity&author=M%20Gato-Canas&author=M%20Zuazo&author=H%20Arasanz&author=M%20Ibanez-Vea&author=L%20Lorenzo&volume=20&issue=8&publication_year=2017&pages=1818-29&pmid=28834746&doi=10.1016/j.celrep.2017.07.075&?
- How much does https://doi.org/10.1172/JCI31422 pull in monthly?
- What's the financial intake of https://scholar.google.com/scholar_lookup?journal=J%20Clin%20Invest&title=Altered%20macrophage%20differentiation%20and%20immune%20dysfunction%20in%20tumor%20development&author=A%20Sica&author=V%20Bronte&volume=117&issue=5&publication_year=2007&pages=1155-66&pmid=17476345&doi=10.1172/JCI31422&?
- How much does https://doi.org/10.1016/j.semcancer.2008.03.004 generate monthly?
- Check the income stats for https://scholar.google.com/scholar_lookup?journal=Semin%20Cancer%20Biol&title=Macrophage%20polarization%20in%20tumour%20progression&author=A%20Sica&author=P%20Larghi&author=A%20Mancino&author=L%20Rubino&author=C%20Porta&volume=18&issue=5&publication_year=2008&pages=349-55&pmid=18467122&doi=10.1016/j.semcancer.2008.03.004&
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- What's the profit of https://doi.org/10.1038/s41590-017-0022-x?
- How much does https://scholar.google.com/scholar_lookup?journal=Nat%20Immunol&title=Myeloid-derived%20suppressor%20cells%20coming%20of%20age&author=F%20Veglia&author=M%20Perego&author=D%20Gabrilovich&volume=19&issue=2&publication_year=2018&pages=108-19&pmid=29348500&doi=10.1038/s41590-017-0022-x& generate monthly?
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- What's the income of https://doi.org/10.18632/oncotarget.12278?
- Discover the revenue of https://scholar.google.com/scholar_lookup?journal=Oncotarget&title=On%20the%20origin%20of%20myeloid-derived%20suppressor%20cells&author=CR%20Millrud&author=C%20Bergenfelz&author=K%20Leandersson&volume=8&issue=2&publication_year=2017&pages=3649-65&pmid=27690299&doi=10.18632/oncotarget.12278&
- How much does https://doi.org/10.1158/0008-5472.CAN-09-2587 gross monthly?
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- Revenue of https://doi.org/10.1038/nri2506
- What's https://scholar.google.com/scholar_lookup?journal=Nat%20Rev%20Immunol&title=Myeloid-derived%20suppressor%20cells%20as%20regulators%20of%20the%20immune%20system&author=DI%20Gabrilovich&author=S%20Nagaraj&volume=9&issue=3&publication_year=2009&pages=162-74&pmid=19197294&doi=10.1038/nri2506&'s gross income?
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- What are the total earnings of https://scholar.google.com/scholar_lookup?journal=J%20Immunol&title=Transcriptional%20profiling%20of%20the%20human%20monocyte-to-macrophage%20differentiation%20and%20polarization:%20new%20molecules%20and%20patterns%20of%20gene%20expression&author=FO%20Martinez&author=S%20Gordon&author=M%20Locati&author=A%20Mantovani&volume=177&issue=10&publication_year=2006&pages=7303-11&pmid=17082649&doi=10.4049/jimmunol.177.10.7303&?
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- What are the total earnings of https://scholar.google.com/scholar_lookup?journal=Trends%20Immunol&title=IDO%20in%20the%20tumor%20microenvironment:%20inflammation,%20counter-regulation,%20and%20tolerance&author=DH%20Munn&author=AL%20Mellor&volume=37&issue=3&publication_year=2016&pages=193-207&pmid=26839260&doi=10.1016/j.it.2016.01.002&?
- Financial intake of https://doi.org/10.1080/2162402X.2017.1344804
- What's the monthly money flow for https://scholar.google.com/scholar_lookup?journal=Oncoimmunology&title=Exogenous%20lipid%20uptake%20induces%20metabolic%20and%20functional%20reprogramming%20of%20tumor-associated%20myeloid-derived%20suppressor%20cells&author=AA%20Al-Khami&author=L%20Zheng&author=L%20Del%20Valle&author=F%20Hossain&author=D%20Wyczechowska&volume=6&issue=10&publication_year=2017&pages=e1344804&pmid=29123954&doi=10.1080/2162402X.2017.1344804&?
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- How much revenue does https://doi.org/10.1126/sciimmunol.aaf8943 produce monthly?
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- https://doi.org/10.1038/cddis.2017.192's total income per month
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- Discover the revenue of https://scholar.google.com/scholar_lookup?journal=J%20Immunol&title=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase%203%20(PFKFB3)%20is%20necessary%20for%20human%20melanoma%20MDSC%20differentiation%20and%20function&author=J%20Grewal&author=J%20Ricthie&author=N%20Al%20Rayyan&author=S%20Telang&author=K%20Yaddanapudi&volume=196&issue=1%20Suppl&publication_year=2016&pages=74.8&
- What's the income generated by https://doi.org/10.1111/imm.12662 each month?
- https://scholar.google.com/scholar_lookup?journal=Immunology&title=Atorvastatin%20promotes%20the%20expansion%20of%20myeloid-derived%20suppressor%20cells%20and%20attenuates%20murine%20colitis&author=A%20Lei&author=Q%20Yang&author=X%20Li&author=H%20Chen&author=M%20Shi&volume=149&issue=4&publication_year=2016&pages=432-46&pmid=27548304&doi=10.1111/imm.12662&'s total income per month
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- Learn how profitable https://scholar.google.com/scholar_lookup?journal=Nat%20Rev%20Immunol&title=Statin%20therapy%20and%20autoimmune%20disease:%20from%20protein%20prenylation%20to%20immunomodulation&author=J%20Greenwood&author=L%20Steinman&author=SS%20Zamvil&volume=6&issue=5&publication_year=2006&pages=358-70&pmid=16639429&doi=10.1038/nri1839& is on a monthly basis
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- https://doi.org/10.1016/j.molmed.2007.11.004's revenue stream
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- What's the income of https://doi.org/10.1002/eji.200838278?
- How much revenue does https://scholar.google.com/scholar_lookup?journal=Eur%20J%20Immunol&title=Simvastatin%20impairs%20humoral%20and%20cell-mediated%20immunity%20in%20mice%20by%20inhibiting%20lymphocyte%20homing,%20T-cell%20activation%20and%20antigen%20cross-presentation&author=C%20Ulivieri&author=D%20Fanigliulo&author=D%20Benati&author=FL%20Pasini&author=CT%20Baldari&volume=38&issue=10&publication_year=2008&pages=2832-44&pmid=18958884&doi=10.1002/eji.200838278& bring in?
- How much does https://doi.org/10.1056/NEJMra1514296 rake in every month?
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- Get to know https://scholar.google.com/scholar_lookup?journal=Mol%20Cell%20Biol&title=Akt-directed%20glucose%20metabolism%20can%20prevent%20Bax%20conformation%20change%20and%20promote%20growth%20factor-independent%20survival&author=JC%20Rathmell&author=CJ%20Fox&author=DR%20Plas&author=PS%20Hammerman&author=RM%20Cinalli&volume=23&issue=20&publication_year=2003&pages=7315-28&pmid=14517300&doi=10.1128/MCB.23.20.7315-7328.2003&'s earnings
- What's https://doi.org/10.1371/journal.pone.0015425's gross income?
- How much revenue does https://scholar.google.com/scholar_lookup?journal=PLoS%20One&title=Induction%20of%20glucose%20metabolism%20in%20stimulated%20T%20lymphocytes%20is%20regulated%20by%20mitogen-activated%20protein%20kinase%20signaling&author=AJ%20Marko&author=RA%20Miller&author=A%20Kelman&author=KA%20Frauwirth&volume=5&issue=11&publication_year=2010&pages=e15425&pmid=21085672&doi=10.1371/journal.pone.0015425& produce monthly?
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- Explore the financials of https://doi.org/10.1016/j.immuni.2016.05.001
- What's the income of https://scholar.google.com/scholar_lookup?journal=Immunity&title=Lag-3,%20Tim-3,%20and%20TIGIT:%20co-inhibitory%20receptors%20with%20specialized%20functions%20in%20immune%20regulation&author=AC%20Anderson&author=N%20Joller&author=VK%20Kuchroo&volume=44&issue=5&publication_year=2016&pages=989-1004&pmid=27192565&doi=10.1016/j.immuni.2016.05.001&?
- What is the monthly revenue of https://doi.org/10.1016/j.immuni.2016.05.002?
- How much cash flow does https://scholar.google.com/scholar_lookup?journal=Immunity&title=Coinhibitory%20pathways%20in%20the%20B7-CD28%20ligand-receptor%20family&author=FA%20Schildberg&author=SR%20Klein&author=GJ%20Freeman&author=AH%20Sharpe&volume=44&issue=5&publication_year=2016&pages=955-72&pmid=27192563&doi=10.1016/j.immuni.2016.05.002& have monthly?
- https://doi.org/10.1084/jem.20090847 income
- How much income is https://scholar.google.com/scholar_lookup?journal=J%20Exp%20Med&title=PD-L1%20regulates%20the%20development,%20maintenance,%20and%20function%20of%20induced%20regulatory%20T%20cells&author=LM%20Francisco&author=VH%20Salinas&author=KE%20Brown&author=VK%20Vanguri&author=GJ%20Freeman&volume=206&issue=13&publication_year=2009&pages=3015-29&pmid=20008522&doi=10.1084/jem.20090847& earning monthly?
- Revenue of https://doi.org/10.1126/science.1160062
- https://scholar.google.com/scholar_lookup?journal=Science&title=CTLA-4%20control%20over%20Foxp3+%20regulatory%20T%20cell%20function&author=K%20Wing&author=Y%20Onishi&author=P%20Prieto-Martin&author=T%20Yamaguchi&author=M%20Miyara&volume=322&issue=5899&publication_year=2008&pages=271-5&pmid=18845758&doi=10.1126/science.1160062&'s revenue stream
- https://doi.org/10.1146/annurev-immunol-032414-112049's revenue stream
- Discover the revenue of https://scholar.google.com/scholar_lookup?journal=Annu%20Rev%20Immunol&title=Coinhibitory%20pathways%20in%20immunotherapy%20for%20cancer&author=SH%20Baumeister&author=GJ%20Freeman&author=G%20Dranoff&author=AH%20Sharpe&volume=34&publication_year=2016&pages=539-73&pmid=26927206&doi=10.1146/annurev-immunol-032414-112049&
- How much does https://doi.org/10.1126/science.1242454 gross monthly?
- Income figures for https://scholar.google.com/scholar_lookup?journal=Science&title=Fueling%20immunity:%20insights%20into%20metabolism%20and%20lymphocyte%20function&author=EL%20Pearce&author=MC%20Poffenberger&author=CH%20Chang&author=RG%20Jones&volume=342&issue=6155&publication_year=2013&pages=1242454&pmid=24115444&doi=10.1126/science.1242454&
- How profitable is https://doi.org/10.1016/j.ccell.2017.08.004?
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- https://doi.org/10.18632/oncotarget.2789 income
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- How much income is https://doi.org/10.15252/embr.201744154 earning monthly?
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- https://scholar.google.com/scholar_lookup?journal=Clin%20Cancer%20Res&title=Activity%20of%20the%20monocarboxylate%20transporter%201%20inhibitor%20AZD3965%20in%20small%20cell%20lung%20cancer&author=R%20Polanski&author=CL%20Hodgkinson&author=A%20Fusi&author=D%20Nonaka&author=L%20Priest&volume=20&issue=4&publication_year=2014&pages=926-37&pmid=24277449&doi=10.1158/1078-0432.CCR-13-2270&'s total income per month
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- How much does https://scholar.google.com/scholar_lookup?journal=Proc%20Natl%20Acad%20Sci%20U%20S%20A&title=CD147%20subunit%20of%20lactate/H+%20symporters%20MCT1%20and%20hypoxia-inducible%20MCT4%20is%20critical%20for%20energetics%20and%20growth%20of%20glycolytic%20tumors&author=R%20Le%20Floch&author=J%20Chiche&author=I%20Marchiq&author=T%20Naiken&author=K%20Ilc&volume=108&issue=40&publication_year=2011&pages=16663-8&pmid=21930917&doi=10.1073/pnas.1106123108& earn?
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- Revenue of https://doi.org/10.1186/s12885-017-3458-3
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Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
- nihcesxway5.hub.nih.gov
Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
- lhcns2.nlm.nih.gov
CDN Services {📦}
- Ncbi