
NCBI . NLM . NIH . GOV {
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Title[redir]:
Axl and MerTK receptor tyrosine kinases maintain human macrophage efferocytic capacity in the presence of viral triggers - PMC
Description:
The requirement to remove apoptotic cells is equally important in homeostasis and inflammatory disease. In particular, during viral infections large quantities of infected cells undergo apoptosis and need to be efficiently cleared by phagocytes to ...
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Keywords {đ}
axl, macrophages, apoptotic, mertk, mdms, cells, cell, expression, viral, human, doi, tam, pubmed, google, scholar, pmc, receptor, efferocytosis, polyic, receptors, article, inflammatory, fig, efferocytic, capacity, information, ifnÎą, data, free, uptake, stimuli, infection, inflammation, macrophage, shown, supporting, infections, gas, stimulated, levels, control, nlm, immunol, tyrosine, tyro, induction, blocking, role, antiinflammatory, protein,
Topics {âď¸}
ďż˝csf/gmâcsfâfree medium magneticâactivated cell sorting 100 ng/ml phrodoâse resulting antiâinflammatory phenotype receptor tyrosine kinases human monocyteâderived macrophages pmc beta search brainâspecific angiogenesis inhibitorâ1 virusâinfected apoptotic cells antiâviral immune responses supporting information fig express high levels apcâconjugated antiâaxl proâinflammatory signals caused axlâexpressing cells accumulate mertk blocking antibody axl blocking antibody systemic lupus erythematosus primary human macrophages 50 ng/ml ifnâÎť apoptotic cell uptake license information pmcid gmâcsfâdifferentiated mdms prevent secondary necrosis monocyteâderived macrophages supplementary materials included tam receptor activation sustains macrophage capacity cell signaling technology expressed high levels apoptotic cell recognition transcriptional programs triggered taqman expression assays apoptotic cell sensors publisher site pdf apoptotic cell clearance engulf apoptotic cells highâcapacity rnaâ mdm efferocytic activity antiâinflammatory responses 7 scavenger receptor cd36 ďż˝csfâdifferentiated mdms stimulated alveolar/airway macrophages inflammatory cell recruitment macrophages contributes significantly influenza virusâinfected protease inhibitor cocktail human alveolar macrophages maintaining macrophage capacity bridging molecule gas6
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