
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Human αβ and γδ T Cells in Skin Immunity and Disease - PMC
Description:
γδ T lymphocytes maintain skin homeostasis by balancing keratinocyte differentiation and proliferation with the destruction of infected or malignant cells. An imbalance in skin-resident T cell function can aggravate skin-related autoimmune diseases, ...
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🌠 Phenomenal Traffic: 5M - 10M visitors per month
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Keywords {🔍}
cells, google, scholar, pubmed, doi, cell, skin, pmc, article, free, human, immunol, alopecia, areata, patients, psoriasis, activation, immune, melanoma, epidermal, receptor, wound, function, expression, dermatol, diabetes, memory, skinresident, lymphocytes, cytokines, blood, production, disease, mice, homeostasis, cytokine, inflammation, cancer, type, growth, express, hair, med, epidermis, adhesion, nat, gamma, immunity, healing, molecules,
Topics {✒️}
gov/diabetes/pdfs/data/statistics/national-diabetes-statistics-report th1/th2/th17 cytokine secretion amp-activated protein kinase long-lived memory form phosphotyrosine-rich aggregates class ii-independent generation psoriasis-specific il-17-producing αβ pmc beta search parallel th17/th22 skewing highlights disease-specific patterns mycobacterium tuberculosis-reactive vg9vd2+ anti-il-12p40 antibody induce fas-mediated cytotoxicity c3h/hej mouse model tumor necrosis factor-alpha pro-inflammatory cytokine genes genome-wide meta-analysis positive-strand rna virus genome-wide association studies genome-wide association study t-resident memory cells chemokine mip-3 alpha/ccl20 pro-inflammatory immune response skin-specific gamma delta anti-tnf-α therapies cells produce ifn-γ skin-resident versus recirculating blocks ifn-γ signaling il-17r helps regulate peripheral t-cell tolerance regulate skin-specific αβ t-cell antigen receptors tissue-resident memory cd8+ mhc class ii open-label pilot study small-cell lung cancer human gamma/delta-positive regulatory t-cell cytokines obesity-linked insulin resistance human skin-homing memory γδ t-cell growth skin produce tnf-α nk-cell derived cytokine cell-mediated skin inflammation immunosuppressive/regulatory roles migrate dermal il-17-producing γδ tissue-resident memory cells cd103-deficient mice show ccl27-ccr10 interactions regulate recent meta-analysis studies
Questions {❓}
- Is alopecia areata an autoimmune-response against melanogenesis-related proteins, exposed by abnormal MHC class I expression in the anagen hair bulb?
- The genetics of type 2 diabetes: what have we learned from GWAS?
- Why is melanoma so metastatic?
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