
NCBI . NLM . NIH . GOV {
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Title[redir]:
Current landscape and future of dual anti-CTLA4 and PD-1/PD-L1 blockade immunotherapy in cancer; lessons learned from clinical trials with melanoma and non-small cell lung cancer (NSCLC) - PMC
Description:
Immunotherapy is among the most rapidly evolving treatment strategies in oncology. The therapeutic potential of immune-checkpoint inhibitors is exemplified by the recent hail of Food and Drug Administration (FDA) approvals for their use in various ...
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Keywords {🔍}
nivo, mgkg, patients, ipi, ipilimumab, nivolumab, phase, doi, therapy, combination, nct, arm, melanoma, weeks, response, treatment, monotherapy, months, trials, pdl, pubmed, google, scholar, checkpoint, nsclc, pfs, cancer, trial, outcomes, rate, immunotherapy, tumor, recruiting, pmc, free, cell, inhibition, article, checkmate, study, combined, ctla, orr, adverse, clinical, events, doses, advanced, cells, tumors,
Topics {✒️}
/press-release/bristolmyers/bristol-myers-squibb-announces-top-line-resultscheckmate-026-phase-3-stu /oncology-times/blog/fdaactionsandupdates/pages/post ipi 3 mg/kg + nivo 1 mg/kg ipi 1 mg/kg + nivo 3 mg/kg ipi 1 mg/kg + nivo 6 mg/kg nivo 1 mg/kg + ipi 3 mg/kg nivo 3 mg/kg + ipi 3 mg/kg nivo 10 mg/kg + ipi 3 mg/kg nivo 10 mg/kg + ipi 10 mg/kg nivo 3 mg/kg + ipi 1 mg/kg tremelimumab 3 mg/kg + medi4736 20 mg/kg 3 mg/kg + ipi 3 mg/kg braf-mutant unresectable/metastatic melanoma ipi 3 mg/kg q3w + placebo braf-v600 kinase inhibitor anti-pd-1/pd-l1 moab targeting pd-1/pd-l1 interactions pd-1/pd-l1 checkpoint inhibitors top-line b-msa anti-ctla-4 immune-checkpoint inhibitor anti-tumor t-cell activity anti–pd-1/pd-l1 therapy anti-ctla-4 immune-checkpoint inhibitors ipi 3 mg/kg q3w nivo 3 mg/kg q2w nivo 3 mg/kg q2w + nivo 3 mg/kg q3w pd-1/pd-l1 blockade immunotherapy /science/article/pii/s1044579x0700034x pan-raf kinase inhibitor anti-lpam-1/α4β7 moab recurrent squamous-cell carcinoma nct02696993 unresectable/metastatic nsclc phase 1 + ipi 1 mg/kg igg4 anti-pd-1 moab anti-pd-l1 moab small-cell lung cancer small-cell lung cancer carboplatin 6 mg/ml/min carboplatin 5 mg/ml/min pd-1/pd-l1 mediated induction immune-related adverse events braf-wild type melanoma immune-checkpoint inhibitors targeting dual-immune checkpoint inhibition pd-l1 mediates peripheral refractory/recurrent solid tumors braf wild-type tumors stage iv melanoma pd-1/pd-l1 inhibition
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