
NCBI . NLM . NIH . GOV {
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Title[redir]:
Magnolol Alleviates Inflammatory Responses and Lipid Accumulation by AMP-Activated Protein Kinase-Dependent Peroxisome Proliferator-Activated Receptor α Activation - PMC
Description:
Magnolol (MG) is a kind of lignin isolated from Magnolia officinalis, which serves several different biological functions, such as antifungal, anticancer, antioxidant, and hepatoprotective functions. This study aimed to evaluate the protective ...
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Keywords {🔍}
cells, protein, doi, pubmed, google, scholar, hepg, expression, ampk, liver, akt, steatosis, lipid, mice, accumulation, oainduced, pparα, kinase, cell, activation, srebpc, results, fatty, µgml, magnolol, pathways, analysis, pmc, effect, hepatic, nfκb, phosphorylation, acc, nafld, inflammatory, mgkg, acid, hyperlipidemia, signaling, disease, group, figure, figures, article, effects, nonalcoholic, min, receptor, treatment, experiments,
Topics {✒️}
p-c-jun n-terminal kinase c-jun n-terminal kinase mg inhibits mapk/nf-κb/srebp-1c hrp-conjugated goat anti-rabbit peroxisome proliferator-activated receptor peroxisome proliferator-activated receptors mitogen-activated protein kinase nrf2/ho-1signaling pathway involves mapk/nf-κb/srebp-1c inhibition enzyme-linked immunosorbent assay measure tnf-α level amp-activated protein kinase oa-induced nf-κb elevation suppressed srebp-1c generation serine/threonine protein kinase enzyme converts acetyl-coa ligand-inducible nuclear receptors mitogen-activated protein pin1-dependent prolyl isomerization inhibit srebp-1c generation mg-inhibited srebp-1c activation pmc beta search goat anti-mouse antibodies nrf2/ho-1 signaling pathway srebp-1c protein expression acetaminophen-induced liver damage induces srebp-1c expression induces tg-rich lipoproteins activated protein kinase suppresses srebp-1c elevation tnf-α activates ameliorated oa-induced phosphorylation p-acc/acc protein expression protein-free surfactant nf-κb signaling pathways oa-induced hepatic steatosis mod = iod/sum area oa-induced phospho-p65 phospho-iκb protein expression tnf-α production tnf-α overproduction upstream protein srebp-1c oa-induced inflammatory response reactive oxygen species tissue-tek oct compound anti-steatosis signaling pathway oa-induced lipid accumulation p-acetyl-coa carboxylase p-p65 protein expression oa-induced hepg2 cells
Questions {❓}
- A lipid to treat non-alcoholic fatty liver disease – The dawn of ‘lipo-rehabilitation’?
- Peroxisome proliferator-activated receptors (PPARs) and PPAR agonists: the ‘future’ in dermatology therapeutics?
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