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Title[redir]:
Pre-45s rRNA promotes colon cancer and is associated with poor survival of CRC patients - PMC
Description:
One characteristic of cancer cells is the abnormally high rate of cell metabolism to sustain their enhanced proliferation. However, the behind mechanism of this phenomenon is still elusive. Here we find that enhanced precursor 45s ribosomal RNA ...
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Keywords {🔍}
rrna, pres, cancer, expression, cells, figure, colon, cell, crc, level, supplementary, data, patients, tumor, hct, knockdown, doi, pubmed, google, scholar, apc, tissues, protein, high, additional, click, file, ribosomal, usa, free, pmc, rna, rpl, tif, camkiiskubf, growth, enhanced, article, lines, levels, normal, compared, signaling, ubf, transcription, hong, kong, upregulation, realtime, pcr,
Topics {✒️}
ribosomal s6 kinase disease-free hazard ratio upstream binding factor ribosomal protein l11 hazard ratio elevated calcium ion uncovered camkii-s6k-ubf axis protein kinase camkii-s6k-ubf axis mediates inducing camkii-s6k-ubf axis calcium ion camkii-s6k-ubf axis mediated t-type calcium channels camkii-s6k-ubf signaling cascade 5′-monophosphate atp-dependent channels tata binding protein double-distilled water camkii-s6k-ubf axis ribosomal protein l5 adenomatous polyposis coli camkii-s6k-ubf mediated cuhk-shenzhen research institute calcium channels present pre-45s rrna transcript inducing mdm2/rpl11 interaction ribosomal s6k sirna pre-45s rrna favored pre-45s rrna possessed pre-45s rrna 5′-ctgacacgctgtcctctggcga-3′ pmc beta search mtor-dependent regulation pre-45s rrna relative pre-45s rrna transcription suppressing mdm2/rpl11 interaction pre-45s rrna correlated pre-45s rrna induced pre-45s rrna mediated pre-45s rrna levels pre-45s rrna expression disease-free hr increases pre-45s rrna pre-45s rrna level wnt/ca2+ signaling pathway 70% ethanol-phosphate-buffered saline mdm2-mediated p53 ubiquitination pre-45s rrna sirna camkii-s6k-ubf causing cell-cycle arrest cell calcium 2006
Questions {❓}
- Does the ribosome translate cancer?
- Mapping the cleavage sites on mammalian pre-rRNAs: Where do we stand?
- Remodelling of Ca2+ transport in cancer: how it contributes to cancer hallmarks?
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