
NCBI . NLM . NIH . GOV {
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Title[redir]:
RARα/RXR Synergism Potentiates Retinoid Responsiveness in Cutaneous T Cell Lymphoma Cell Lines - PMC
Description:
Retinoids, natural and synthetic derivatives of vitamin A, induce cellular changes by activating nuclear retinoic acid receptors (RAR) and retinoid X receptors (RXR). Although the ability of retinoids to govern gene expression is exploited ...
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Keywords {🔍}
cell, ctcl, cells, doi, receptor, bexarotene, google, scholar, pubmed, receptors, rar, retinoid, rarα, expression, adhesion, apoptosis, retinoids, rxr, rarαrxr, hut, hrs, lines, acid, activation, journal, lymphoma, exposure, pmc, cutaneous, cancer, agonists, synergism, responses, proliferation, clinical, fig, retinoic, integrin, agonist, nuclear, human, atra, tcell, article, gene, isotype, selective, line, cellular, multiple,
Topics {✒️}
goat anti-rat igg real-time quantitative pcr cutaneous t-cell lymphoma 37% formalin/1×phosphate-buffered saline rarα/rxr synergism induced methods cell culture increasing β7-mediated adhesion minimizing adverse side-effects increase β7-dependent adhesion advancing retinoid-based approaches genuine rar/rxr agonism rxr selective pan-agonist peroxisome proliferator-activated receptors skin-derived chemokine signals peroxisome proliferator-activated receptor pmc beta search increased α4-subunit abundance pan-rxr activator sr11237 average a405=average a405 annexin v-fitc mucosal-derived trafficking signals fluorescein-conjugated antibody rar isotype-specific agonist integrin β7-ligand madcam-1 rarα-mediated transcriptional activation rarα/rxr activation resulted rar isotype-specific agonists anti β-tubulin mab fluorescent secondary antibody p-nitrophenyl phosphate rarα/rxr synergism bexarotene-induced ctcl apoptosis rarα/rxr coactivation rxrs induces apoptosis synergism induced apoptosis human integrin α4 publisher site pdf rarα/rxr activity integrin β7 expression rxr selective agonist rar/rxr heterodimers detrimental side effects β7 transcript levels brdu proliferation assays β7-dependent functional rxr selective activators retinoic acid receptors dual agonism cell adhesion molecule rxr receptors overcame
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