
NCBI . NLM . NIH . GOV {
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Title[redir]:
Stepwise assembly of functional Câterminal REST/NRSF transcriptional repressor complexes as a drug target - PMC
Description:
In human cells, thousands of predominantly neuronal genes are regulated by the repressor element 1 (RE1)âsilencing transcription factor/neuronârestrictive silencer factor (REST/NRSF). REST/NRSF represses transcription of these genes in stem cells ...
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Keywords {đ}
restnrsf, cells, crc, complex, doi, fig, pubmed, google, scholar, protein, hdac, cell, lsd, corest, proteins, expression, buffer, pmc, renrse, system, histone, activity, gel, fulllength, article, min, medulloblastoma, incubated, repressor, human, purification, medium, free, complexes, added, genes, collected, shown, antiflag, factor, molecular, purified, sites, domain, inhibitors, days, supernatant, transcription, drugs, production,
Topics {âď¸}
re1/neuronârestrictive silencer element neuronârestrictive silencer factor eglâ27âmta1 homology 2 lysogeny broth bocâacâlysâamc substrate [fig switchingâdefective protein 3 40 Îźg/ml 5âbromoâ4âchloroâ3âindolylâβâ relative light units transcriptionâfactorâmediated epigenetic control ďż˝gal 5âbromoâ4âchloroâ3âindolylâβâ common silencer element coomassieâstained sdsâpage gel restmâcorestâlsd1âhdac1 fullâlength complex lysineâspecific demethylase 1a betaâtrcpârestâmad2 axis multiple neuronâspecific genes coomassieâstained sdsâpage gels cellâtypeâspecific gene profile fullâlength corestâlsd1âhdac1 complex corestâlsd1âhdac1 fullâlength complex amino oxidase domain rest/nrsfâcorestâlsd1 comigrated [fig brainâderived neurotrophic factor relative fluorescence units krĂźppelâtype zinc finger fullâlength human rest/nrsf human fullâlength rest/nrsf lysineâspecific demethylase 1 rest/nrsf binds sequenceâspecifically rest/nrsf represses transcription protein concentrationâdependent bandâshift cytoplasmic extract 1Ă penicillin/streptomycin neuronâspecific splicing repressor element 1 powerful transcription factor canonical re1/nrse site neuralâspecific gene expression neural stem/progenitor cells halfâsite re1/nrse half site re1/nrse halfâsite re1s/nrses neuralâspecific gene regulation antiâflag immunoaffinity chromatography mammalian silencer protein neuronal repressor rest/nrsf 5Ă tris/borate/edta ďż˝1âthiogalactopyranoside fullâlength rest/nrsf pmc beta search
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Analytics and Tracking {đ}
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