
NCBI . NLM . NIH . GOV {
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Title[redir]:
Activation of the complement system generates antibacterial peptides - PMC
Description:
The complement system represents an evolutionary old and significant part of the innate immune system involved in protection against invading microorganisms. Here, we show that the anaphylatoxin C3a and its inactivated derivative C3a-desArg are ...
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Keywords {๐}
peptides, fig, pubmed, google, scholar, doi, cny, peptide, antibacterial, bacteria, aeruginosa, cadesarg, bacterial, incubated, activity, heparin, membranes, tris, complement, antimicrobial, min, pmc, amps, shown, human, lge, activities, fluorescence, effects, concentrations, control, caderived, washed, system, faecalis, pyogenes, obtained, lrk, cnys, analysis, binding, concentration, nlm, article, coli, liposomes, cells, fragments, determined, conditions,
Topics {โ๏ธ}
poly-l-lysine-coated cover glass poly-l-lysine-coated nylaflo high-numerical-aperture oil-condenser positive-ion/delayed-extraction mode formvar-coated copper grids maldi-tof ms analysis freezeโthaw cycles consisting inactivated derivative c3a-desarg defined helix-forming segment pmc beta search western blot analysis anti-lge27 antibody showed c3a-derived peptides required colony-forming units synthetic c3a-derived peptides gram-positive enterococcus faecalis c3a-derived peptide lge27 viable-count analysis characterize heparin-binding peptides publisher site pdf lower organisms lacking inactive c3a-desarg peptide c3a-desarg bind heparin possess chemotactic activity viable-count assays license information pmcid interactions promote conformational direct antibacterial role gram-positive species c3a cleavage products molecular-mass markers molecular mass markers kinetic analysis showed n-terminal sequencing streptococcus pyogenes ap1 direct bacterial killing membrane permeabilizing effect nonspecific host response smooth-muscle contraction increased vascular permeability chronic venous ulcers trypticase soy broth holmโsidak method avanti polar lipids axis-shield po 75โ100 single-shot measurements oxidative burst response tunicate pyura stolonifera expert technical assistance royal physiographic society
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