
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Targeting estrogen receptor signaling with fulvestrant enhances immune and chemotherapy-mediated cytotoxicity of human lung cancer - PMC
Description:
The conversion of tumor cells from an epithelial to a mesenchymal-like phenotype, via a process designated as the epithelial-mesenchymal transition (EMT), is known to mediate tumor resistance to a variety of cell death inducers, including cytotoxic ...
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Keywords {🔍}
cells, cancer, lung, doi, fulvestrant, esr, tumor, expression, estrogen, fig, cell, lysis, google, scholar, pubmed, receptor, emt, brachyury, resistance, mesenchymal, carcinoma, pmc, levels, article, mesenchymallike, immunemediated, trail, signaling, cytotoxic, compounds, shown, mrna, free, treated, analysis, observed, fibronectin, activity, control, treatment, epithelial, features, chemotherapy, susceptibility, chemoresistant, immune, high, response, data, association,
Topics {✒️}
cis/vin-resistant h1703 cells antagonizing p53-mediated apoptosis cis/vin-resistant h460 cells tumor-positive estrogen receptor-alpha full-length human brachyury hla-a24-restricted mucin-1 single brachyury-binding site small molecule-targeted therapies tissue-specific transcription factor small-cell lung cancer female immune-compromised mice quantitative high-throughput screening single cell-derived culture immune-mediated lytic assays enhancing immune-mediated lysis improving immune-mediated lysis chemo-resistant h1703 cells h1703 chemo-resistant cells pmc beta search chemo-resistant h460 cells quantitative high-throughput screen brachyury-reporter vector treated t-cell-mediated lysis custom grid-based algorithm immune-mediated cytotoxicity observed enhance immune-mediated lysis cis/vin-resistant luciferase reporter vector dose-response curve data serum-free medium [google scholar] 39 methods cell lines clonal h460 esr1-high brachyury-specific cd8+ cytotoxic small-molecule compounds h460 cell line single clonal populations trail receptors trail-r1 established cell lines low esr1 groups supplementary materials included publisher site pdf h460 esr1-high clone h460 esr1-low clone high-throughput screening dose-dependent manner dose-dependent fashion immune-effector mechanisms immune effector mechanisms license information pmcid
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Analytics and Tracking {📊}
- Google Analytics
- Google Analytics 4
- Google Tag Manager
Libraries {📚}
- jQuery
- jQuery module (jquery-3.6.0)
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
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Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
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CDN Services {📦}
- Ncbi