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Keywords {🔍}

smad, ihh, growth, mice, fig, chondrocytes, pubmed, google, scholar, doi, tgfβ, mutants, double, levels, plate, control, smadcko, cells, mutant, signaling, smadfxfx, rna, promoter, cell, pmc, expression, article, cartilage, zone, zones, hdac, free, resting, snon, activity, protein, increased, prehypertrophic, data, chondrocyte, binding, ski, hypertrophic, plates, tif, columnar, analysis, differentiation, smads, performed,

Topics {✒️}

mixed c57bl/6j/cd1 background transforming growth factor-beta pmc beta search tgf-beta induces assembly sequence-specific transcription activators parathyroid hormone-related peptide chip-chip/chip-seq studies mutated ihh742-luc activity goat anti-rabbit green form hetero-oligomeric complexes mediating signal cross-talk blue double-headed arrows quantitative phospho-smad2 levels s2fx/fx = smad2fx/fx goat anti-rabbit red committed col2a1-expressing chondrocytes dual-luciferase reporter assay canonical smad-dependent pathway goat anti-mouse red article published online control smad2fx/fx littermates chip-chip/chip-seq [70] quantitative pcr analysis tgf-β signaling growth factor reveals mutant ihh-promoter constructs tgf-beta signaling supporting information files smad2/3-dependent signaling mediated control smad2fx/fx mice hrp–conjugated secondary antibody mutant constructs m1-luc stimulates cell proliferation mediating tgfβ/activin signaling graded nodal signals cell fate decisions canonical smad-independent pathways control smad2fx/fx chondrocytes limb bud mesenchyme smad2/smad3-dependent manner [54] psii recognition sites canonical smad2/3-mediated signaling sybr green reagent beta-catenin signaling high throughput determination data availability statement chondrocyte terminal differentiation double-headed arrows 742bp ihh construct smad3-deficient neonatal chondrocytes

Social Networks {👍}(6)

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External Links {🔗}(157)

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