
NCBI . NLM . NIH . GOV {
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Title[redir]:
Evolution of acute myelogenous leukemia stem cell properties after treatment and progression - PMC
Description:
Using AML as a model, we investigated the effect of treatment and disease evolution on functionally defined cancer stem cell populations. We demonstrate large-scale changes in LSC frequency and phenotype after relapse, best described using ...
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Keywords {🔍}
relapse, lsc, aml, doi, cells, populations, diagnosis, cell, stem, patients, leukemia, google, scholar, pubmed, frequency, samples, activity, pmc, human, acute, article, figure, population, cdcd, data, supplemental, free, leukemic, myeloid, blood, disease, defined, mice, expression, cancer, increase, paired, sorted, surface, analysis, highdimensional, lscs, engraftment, analyses, tim, table, therapy, identified, performed, antigens,
Topics {✒️}
nod-scid il2rgnull-3/gm/sf mice nod/scid/il2rγc-deficient mice anti-cd38 antibody-mediated clearance high-dimensional mass cytometry 2-tailed mann-whitney test jensen-shannon divergence test high-dimensional data analytics jensen-shannon divergence score fluorescent-labeled cell sorting monoclonal antibody-mediated targeting cancer stem cells--perspectives high-dimensional space analyses lymphoblastic leukaemia-propagating cells pmc beta search acute myelogenous leukemia acute myeloid leukemia large-scale genomic instability nod/scid/il2rγ−/− drug-resistant/refractory disease hematopoietic stem cell offering high-level engraftment blood web site mouse anti-human antibodies high-dimensional space xenotransplantation/limiting dilution analysis chronic myelogenous leukemia cell stem cell leukemia stem cells primitive hematopoietic cell mass cytometry brings anti-human cd45 stem cell research cancer stem cells leukemia-initiating cells represent therapy-refractory reservoirs high-dimensional analysis [google scholar] 14 leukemic stem cells wilmot cancer center clinical drug resistance multiple biological properties cd123+cd34+cd38− population increased primary recipient marrow demonstrate large-scale positively engrafted mice anti-human cd19 traditional flow cytometry early clinical studies page charge payment limiting dilution analyses
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