
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity - PMC
Description:
Extracellular interaction between programmed death ligand-1 (PD-L1) and programmed cell death protein-1 (PD-1) leads to tumour-associated immune escape. Here we show that the immunosuppression activity of PD-L1 is stringently modulated by ...
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Keywords {🔍}
pdl, fig, cells, cell, protein, supplementary, expression, gskβ, cancer, doi, pubmed, google, scholar, glycosylation, analysis, pmc, tumour, article, western, gefitinib, phosphorylation, free, blot, usa, antibody, treated, tcell, antibodies, shown, data, egf, nonglycosylated, breast, mouse, results, treatment, degradation, growth, performed, immune, human, antipd, stabilization, death, glycosylated, mice, programmed, activity, inhibition, stability,
Topics {✒️}
pgipz-shmpd-l1/flag-mpd-l1 pgipz-shpd-l1/pd-l1 4nq mutant pgipz-shpd-l1/pd-l1 3sa mutant human t-cell-mediated cytolysis pgipz-shpd-l1/pd-l1 wt pcdh/pd-l1-flag expression vector t-cell-meditated killing single-agent anti-programmed death-1 reconstitute flag-pd-l1 simultaneously small-molecule glycan-based drugs gsk3β-mediated pd-l1 degradation nano lc-ms/ms analysis inhibits t-cell immunity egfr-mediated pd-l1 stabilization gsk3β-mediated pd-l1 phosphorylation egf-mediated pd-l1 stabilization egf-mediated pd-l1 induction pd-l1 stabilizes pd-l1 pd-l1 4nq/3sa exhibit lc-ms/ms-based identification egf-induced pd-l1 expression pd-l1-expressing bt549 cells unlike ifnγ-induced pd-l1 pd-l1 3sa-expressing cells top-speed-mode cycle time pmc beta search cd3+ t-cell populations pd-l1 amino-acid sequences full-length pd-l1 confocal laser-scanning microscope combat blbc-mediated immunosuppression ubiquitination-mediated protein degradation pd-l1 prevents gsk3β box protein beta-trcp1 anti-pd-1 antibody-treated mice wnt/beta-catenin signaling flag-tagged pd-l1 establish pd-l1-flag gsk-3beta-mediated phosphorylation international research-intensive centers purified human pd-l1 anti-pd-1 antibody-treated balb/ side-chain acceptor located phosphorylation-dependent twist1 degradation real-time pcr machine human pd-l1 clone carbohydrate-based vaccines consisting stabilizes pd-l1 expression reduces pd-l1 expression immune-complex kinase assay
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Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
- nihcesxway5.hub.nih.gov
Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
- lhcns2.nlm.nih.gov
CDN Services {📦}
- Ncbi