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Keywords {🔍}

pitx, doi, fig, data, yap, nrf, hearts, genes, extended, heart, pmc, dpr, pubmed, google, scholar, article, regeneration, control, cells, pitxcko, free, response, lado, pitxoe, ros, resection, figure, binding, cell, cardiomyocyte, apex, open, tab, showed, injury, chipseq, performed, treatment, antioxidant, expression, ventricles, adult, statistical, test, mannwhitney, revealed, nature, target, blue, quantified,

Topics {✒️}

administrated n-acetyl-l-cysteine gov/geo/query/acc supplementary materials included amino-terminal neh2 domain hippo-deficient cardiac regeneration purified glutathione s-transferase hippo-deficient cardiomyocyte renewal regenerating hippo-deficient heart4 wilcoxon signed-rank test pmc beta search adult hippo-deficient hearts pitx2-targeted gene promoters genome-wide enhancer usage trichrome-stained apical areas reactive oxygen species cre-activated pitx2c gain embryonic stem cells tead dna-binding motifs pitx2-induced myocardial regeneration nrf2-activated pitx2 transcription trichrome-stained cross sections function transgenic line components including ndufb3 nuclei-localized pitx2 quantified flag-epitope-tagged pitx2 performed yap chip-seq pitx2-yap interaction important heart specific enhancers common target genes h3k4me3 chromatin marks common human arrhythmia7 pitx2 promotes regeneration adult heart regeneration neonatal mouse heart human mitochondrial disorders direct target genes antioxidant scavenger genes neonatal heart regeneration hippo-deficient ventricles apical border zone nat cell biol hippo-deficient hearts neonatal myocardial regeneration expresses endogenous levels mouse phenotyping core promote myocardial regeneration hippo-deficient mice license information pmcid confer reparative capacity tata-binding protein

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